Gangliogliomas involving the optic chiasm

G. T. Liu*, S. L. Galetta, L. B. Rorke, L. T. Bilaniuk, D. D. Vojta, P. T. Molloy, P. C. Phillips, M. Needle, A. C. Duhaime, L. N. Sutton, N. J. Volpe

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

33 Scopus citations

Abstract

We report three patients with gangliogliomas involving the optic chiasm via distinct mechanisms. The ganglioglioma in one patient likely originated in the temporal lobe and spread medially to involve the chiasm, and diffuse spinal cord dissemination also occurred. Chiasmal involvement in this manner and dissemination at presentation are unusual for gangliogliomas. The tumor in a second patient was intrinsic to the hypothalmus and chiasm, while in the third patient, it involved both optic tracts, and a cyst compressed the chiasm laterally. Two patients developed severe bilateral visual loss, while the other had a stable bitemporal hemianopsia. Two patients received radiotherapy, but one continued to lose vision. Although gangliogliomas rarely involve chiasm, the mechanisms by which they produce chiasmal visual less may be diverse, and the long-term visual prognosis is variable.

Original languageEnglish (US)
Pages (from-to)1669-1673
Number of pages5
JournalNeurology
Volume46
Issue number6
DOIs
StatePublished - Jan 1 1996

ASJC Scopus subject areas

  • Clinical Neurology

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