TY - JOUR
T1 - Gaps in clinical research in frontotemporal dementia
T2 - A call for diversity and disparities–focused research
AU - for the ISTAART FTD PIA and ISTAART Diversity and Disparities PIA
AU - Franzen, Sanne
AU - Nuytemans, Karen
AU - Bourdage, Renelle
AU - Caramelli, Paulo
AU - Ellajosyula, Ratnavalli
AU - Finger, Elizabeth
AU - Illán-Gala, Ignacio
AU - Loi, Samantha M.
AU - Morhardt, Darby
AU - Pijnenburg, Yolande
AU - Rascovsky, Katya
AU - Williams, Monique M.
AU - Yokoyama, Jennifer S.
AU - Alladi, Suvarna
AU - Ayhan, Yavuz
AU - Broce, Iris
AU - Castro-Suarez, Sheila
AU - Coleman, Kristy
AU - de Souza, Leonardo Cruz
AU - Dacks, Penny A.
AU - de Boer, Sterre C.M.
AU - de Leon, Jessica
AU - Dodge, Shana
AU - Grasso, Stephanie
AU - Gupta, Veer
AU - Gupta, Vivek
AU - Ghoshal, Nupur
AU - Kamath, Vidyulata
AU - Kumfor, Fiona
AU - Matias-Guiu, Jordi A.
AU - Narme, Pauline
AU - Nielsen, T. Rune
AU - Okhuevbie, Daniel
AU - Piña-Escudero, Stefanie D.
AU - Garcia, Ramiro Ruiz
AU - Scarioni, Marta
AU - Slachevsky, Andrea
AU - Suarez-Gonzalez, Aida
AU - Tee, Boon Lead
AU - Tsoy, Elena
AU - Ulugut, Hülya
AU - Babulal, Ganesh M.
AU - Onyike, Chiadi U.
N1 - Publisher Copyright:
© 2023 The Authors. Alzheimer's & Dementia published by Wiley Periodicals LLC on behalf of Alzheimer's Association.
PY - 2023
Y1 - 2023
N2 - Frontotemporal dementia (FTD) is one of the leading causes of dementia before age 65 and often manifests as abnormal behavior (in behavioral variant FTD) or language impairment (in primary progressive aphasia). FTD's exact clinical presentation varies by culture, language, education, social norms, and other socioeconomic factors; current research and clinical practice, however, is mainly based on studies conducted in North America and Western Europe. Changes in diagnostic criteria and procedures as well as new or adapted cognitive tests are likely needed to take into consideration global diversity. This perspective paper by two professional interest areas of the Alzheimer's Association International Society to Advance Alzheimer's Research and Treatment examines how increasing global diversity impacts the clinical presentation, screening, assessment, and diagnosis of FTD and its treatment and care. It subsequently provides recommendations to address immediate needs to advance global FTD research and clinical practice.
AB - Frontotemporal dementia (FTD) is one of the leading causes of dementia before age 65 and often manifests as abnormal behavior (in behavioral variant FTD) or language impairment (in primary progressive aphasia). FTD's exact clinical presentation varies by culture, language, education, social norms, and other socioeconomic factors; current research and clinical practice, however, is mainly based on studies conducted in North America and Western Europe. Changes in diagnostic criteria and procedures as well as new or adapted cognitive tests are likely needed to take into consideration global diversity. This perspective paper by two professional interest areas of the Alzheimer's Association International Society to Advance Alzheimer's Research and Treatment examines how increasing global diversity impacts the clinical presentation, screening, assessment, and diagnosis of FTD and its treatment and care. It subsequently provides recommendations to address immediate needs to advance global FTD research and clinical practice.
KW - cultural diversity
KW - diagnosis
KW - ethnicity
KW - frontotemporal dementia
KW - language
KW - literacy
KW - neuropsychological tests
KW - primary progressive aphasia
UR - http://www.scopus.com/inward/record.url?scp=85161401501&partnerID=8YFLogxK
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U2 - 10.1002/alz.13129
DO - 10.1002/alz.13129
M3 - Article
C2 - 37270665
AN - SCOPUS:85161401501
SN - 1552-5260
JO - Alzheimer's and Dementia
JF - Alzheimer's and Dementia
ER -
