Gastroesophageal reflux disease

Sabine Roman*, Peter J. Kahrilas

*Corresponding author for this work

Research output: Chapter in Book/Report/Conference proceedingChapter

Abstract

Gastroesophageal' reflux disease (GERD) is a "condition that develops when the reflux of stomach contents causes troublesome symptoms and/or complications". Since the criteria used to define GERD in epidemiological studies differ from the Montreal definition, it is difficult to know the actual prevalence of GERD in the general population. GERD is usually a clinical diagnosis based on a symptom assessment. Testing is reserved for cases in which there are warning signs of complication, atypical symptoms such that the diagnosis is in doubt, an inadequate response to medical treatment, or as a preoperative evaluation to confirm the diagnosis prior to surgical treatment. Histologic examination of distal esophageal mucosal biopsies might increase the diagnostic yield of endoscopy for GERD. Identification of reflux episodes using pH-metry or pH-impedance monitoring is the accepted reference standard for GERD diagnosis.

Original languageEnglish (US)
Title of host publicationEvidence-based Gastroenterology and Hepatology
Publisherwiley
Pages3-20
Number of pages18
ISBN (Electronic)9781119211419
ISBN (Print)9781119211389
DOIs
StatePublished - Mar 5 2019

Keywords

  • Clinical diagnosis
  • Epidemiological studies
  • Gastroesophageal reflux disease
  • Surgical treatment
  • Symptom assessment

ASJC Scopus subject areas

  • General Medicine

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