Gastrointestinal Complications Associated with Hepatic Arterial Yttrium-90 Microsphere Therapy{A figure is presented}

Ravi Murthy*, Daniel B. Brown, Riad Salem, Steven G. Meranze, Douglas M. Coldwell, Sunil Krishnan, Rodolfo Nunez, Amit Habbu, David Liu, William Ross, Alan M. Cohen, Michael Censullo

*Corresponding author for this work

Research output: Contribution to journalArticle

125 Citations (Scopus)

Abstract

Hepatic arterial therapy with yttrium-90 microspheres exploits the avenue provided by the neoplastic microvasculature to deliver high-energy, low-penetrating therapeutic doses of radiation. Variant hepatic arterial anatomy, collateral vessels, and changes in flow dynamics during treatment can affect particle dispersion and lead to nontarget particle distribution and subsequent gastrointestinal morbidity. Awareness of these variances and techniques to prevent gastrointestinal tract microsphere delivery is essential in mitigating this serious complication. Our aim is to increase the understanding of the role of various imaging and preventative techniques in minimizing this undesired effect.

Original languageEnglish (US)
Pages (from-to)553-561
Number of pages9
JournalJournal of Vascular and Interventional Radiology
Volume18
Issue number4
DOIs
StatePublished - Apr 1 2007

Fingerprint

Yttrium
Microspheres
Liver
Microvessels
Gastrointestinal Tract
Anatomy
Radiation
Morbidity
Therapeutics

ASJC Scopus subject areas

  • Radiology Nuclear Medicine and imaging
  • Cardiology and Cardiovascular Medicine

Cite this

Murthy, Ravi ; Brown, Daniel B. ; Salem, Riad ; Meranze, Steven G. ; Coldwell, Douglas M. ; Krishnan, Sunil ; Nunez, Rodolfo ; Habbu, Amit ; Liu, David ; Ross, William ; Cohen, Alan M. ; Censullo, Michael. / Gastrointestinal Complications Associated with Hepatic Arterial Yttrium-90 Microsphere Therapy{A figure is presented}. In: Journal of Vascular and Interventional Radiology. 2007 ; Vol. 18, No. 4. pp. 553-561.
@article{faa131016e2a47539f7863368a17a467,
title = "Gastrointestinal Complications Associated with Hepatic Arterial Yttrium-90 Microsphere Therapy{A figure is presented}",
abstract = "Hepatic arterial therapy with yttrium-90 microspheres exploits the avenue provided by the neoplastic microvasculature to deliver high-energy, low-penetrating therapeutic doses of radiation. Variant hepatic arterial anatomy, collateral vessels, and changes in flow dynamics during treatment can affect particle dispersion and lead to nontarget particle distribution and subsequent gastrointestinal morbidity. Awareness of these variances and techniques to prevent gastrointestinal tract microsphere delivery is essential in mitigating this serious complication. Our aim is to increase the understanding of the role of various imaging and preventative techniques in minimizing this undesired effect.",
author = "Ravi Murthy and Brown, {Daniel B.} and Riad Salem and Meranze, {Steven G.} and Coldwell, {Douglas M.} and Sunil Krishnan and Rodolfo Nunez and Amit Habbu and David Liu and William Ross and Cohen, {Alan M.} and Michael Censullo",
year = "2007",
month = "4",
day = "1",
doi = "10.1016/j.jvir.2007.02.002",
language = "English (US)",
volume = "18",
pages = "553--561",
journal = "Journal of Vascular and Interventional Radiology",
issn = "1051-0443",
publisher = "Elsevier Inc.",
number = "4",

}

Murthy, R, Brown, DB, Salem, R, Meranze, SG, Coldwell, DM, Krishnan, S, Nunez, R, Habbu, A, Liu, D, Ross, W, Cohen, AM & Censullo, M 2007, 'Gastrointestinal Complications Associated with Hepatic Arterial Yttrium-90 Microsphere Therapy{A figure is presented}', Journal of Vascular and Interventional Radiology, vol. 18, no. 4, pp. 553-561. https://doi.org/10.1016/j.jvir.2007.02.002

Gastrointestinal Complications Associated with Hepatic Arterial Yttrium-90 Microsphere Therapy{A figure is presented}. / Murthy, Ravi; Brown, Daniel B.; Salem, Riad; Meranze, Steven G.; Coldwell, Douglas M.; Krishnan, Sunil; Nunez, Rodolfo; Habbu, Amit; Liu, David; Ross, William; Cohen, Alan M.; Censullo, Michael.

In: Journal of Vascular and Interventional Radiology, Vol. 18, No. 4, 01.04.2007, p. 553-561.

Research output: Contribution to journalArticle

TY - JOUR

T1 - Gastrointestinal Complications Associated with Hepatic Arterial Yttrium-90 Microsphere Therapy{A figure is presented}

AU - Murthy, Ravi

AU - Brown, Daniel B.

AU - Salem, Riad

AU - Meranze, Steven G.

AU - Coldwell, Douglas M.

AU - Krishnan, Sunil

AU - Nunez, Rodolfo

AU - Habbu, Amit

AU - Liu, David

AU - Ross, William

AU - Cohen, Alan M.

AU - Censullo, Michael

PY - 2007/4/1

Y1 - 2007/4/1

N2 - Hepatic arterial therapy with yttrium-90 microspheres exploits the avenue provided by the neoplastic microvasculature to deliver high-energy, low-penetrating therapeutic doses of radiation. Variant hepatic arterial anatomy, collateral vessels, and changes in flow dynamics during treatment can affect particle dispersion and lead to nontarget particle distribution and subsequent gastrointestinal morbidity. Awareness of these variances and techniques to prevent gastrointestinal tract microsphere delivery is essential in mitigating this serious complication. Our aim is to increase the understanding of the role of various imaging and preventative techniques in minimizing this undesired effect.

AB - Hepatic arterial therapy with yttrium-90 microspheres exploits the avenue provided by the neoplastic microvasculature to deliver high-energy, low-penetrating therapeutic doses of radiation. Variant hepatic arterial anatomy, collateral vessels, and changes in flow dynamics during treatment can affect particle dispersion and lead to nontarget particle distribution and subsequent gastrointestinal morbidity. Awareness of these variances and techniques to prevent gastrointestinal tract microsphere delivery is essential in mitigating this serious complication. Our aim is to increase the understanding of the role of various imaging and preventative techniques in minimizing this undesired effect.

UR - http://www.scopus.com/inward/record.url?scp=34147190131&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=34147190131&partnerID=8YFLogxK

U2 - 10.1016/j.jvir.2007.02.002

DO - 10.1016/j.jvir.2007.02.002

M3 - Article

C2 - 17446547

AN - SCOPUS:34147190131

VL - 18

SP - 553

EP - 561

JO - Journal of Vascular and Interventional Radiology

JF - Journal of Vascular and Interventional Radiology

SN - 1051-0443

IS - 4

ER -