Gastrointestinal Complications Associated with Hepatic Arterial Yttrium-90 Microsphere Therapy{A figure is presented}

Ravi Murthy*, Daniel B. Brown, Riad Salem, Steven G. Meranze, Douglas M. Coldwell, Sunil Krishnan, Rodolfo Nunez, Amit Habbu, David Liu, William Ross, Alan M. Cohen, Michael Censullo

*Corresponding author for this work

Research output: Contribution to journalArticle

125 Scopus citations

Abstract

Hepatic arterial therapy with yttrium-90 microspheres exploits the avenue provided by the neoplastic microvasculature to deliver high-energy, low-penetrating therapeutic doses of radiation. Variant hepatic arterial anatomy, collateral vessels, and changes in flow dynamics during treatment can affect particle dispersion and lead to nontarget particle distribution and subsequent gastrointestinal morbidity. Awareness of these variances and techniques to prevent gastrointestinal tract microsphere delivery is essential in mitigating this serious complication. Our aim is to increase the understanding of the role of various imaging and preventative techniques in minimizing this undesired effect.

Original languageEnglish (US)
Pages (from-to)553-561
Number of pages9
JournalJournal of Vascular and Interventional Radiology
Volume18
Issue number4
DOIs
StatePublished - Apr 1 2007

ASJC Scopus subject areas

  • Radiology Nuclear Medicine and imaging
  • Cardiology and Cardiovascular Medicine

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    Murthy, R., Brown, D. B., Salem, R., Meranze, S. G., Coldwell, D. M., Krishnan, S., Nunez, R., Habbu, A., Liu, D., Ross, W., Cohen, A. M., & Censullo, M. (2007). Gastrointestinal Complications Associated with Hepatic Arterial Yttrium-90 Microsphere Therapy{A figure is presented}. Journal of Vascular and Interventional Radiology, 18(4), 553-561. https://doi.org/10.1016/j.jvir.2007.02.002