Abstract
Hepatic arterial therapy with yttrium-90 microspheres exploits the avenue provided by the neoplastic microvasculature to deliver high-energy, low-penetrating therapeutic doses of radiation. Variant hepatic arterial anatomy, collateral vessels, and changes in flow dynamics during treatment can affect particle dispersion and lead to nontarget particle distribution and subsequent gastrointestinal morbidity. Awareness of these variances and techniques to prevent gastrointestinal tract microsphere delivery is essential in mitigating this serious complication. Our aim is to increase the understanding of the role of various imaging and preventative techniques in minimizing this undesired effect.
| Original language | English (US) |
|---|---|
| Pages (from-to) | 553-561 |
| Number of pages | 9 |
| Journal | Journal of Vascular and Interventional Radiology |
| Volume | 18 |
| Issue number | 4 |
| DOIs | |
| State | Published - Apr 1 2007 |
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ASJC Scopus subject areas
- Radiology Nuclear Medicine and imaging
- Cardiology and Cardiovascular Medicine
Cite this
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Gastrointestinal Complications Associated with Hepatic Arterial Yttrium-90 Microsphere Therapy{A figure is presented}. / Murthy, Ravi; Brown, Daniel B.; Salem, Riad; Meranze, Steven G.; Coldwell, Douglas M.; Krishnan, Sunil; Nunez, Rodolfo; Habbu, Amit; Liu, David; Ross, William; Cohen, Alan M.; Censullo, Michael.
In: Journal of Vascular and Interventional Radiology, Vol. 18, No. 4, 01.04.2007, p. 553-561.Research output: Contribution to journal › Article
TY - JOUR
T1 - Gastrointestinal Complications Associated with Hepatic Arterial Yttrium-90 Microsphere Therapy{A figure is presented}
AU - Murthy, Ravi
AU - Brown, Daniel B.
AU - Salem, Riad
AU - Meranze, Steven G.
AU - Coldwell, Douglas M.
AU - Krishnan, Sunil
AU - Nunez, Rodolfo
AU - Habbu, Amit
AU - Liu, David
AU - Ross, William
AU - Cohen, Alan M.
AU - Censullo, Michael
PY - 2007/4/1
Y1 - 2007/4/1
N2 - Hepatic arterial therapy with yttrium-90 microspheres exploits the avenue provided by the neoplastic microvasculature to deliver high-energy, low-penetrating therapeutic doses of radiation. Variant hepatic arterial anatomy, collateral vessels, and changes in flow dynamics during treatment can affect particle dispersion and lead to nontarget particle distribution and subsequent gastrointestinal morbidity. Awareness of these variances and techniques to prevent gastrointestinal tract microsphere delivery is essential in mitigating this serious complication. Our aim is to increase the understanding of the role of various imaging and preventative techniques in minimizing this undesired effect.
AB - Hepatic arterial therapy with yttrium-90 microspheres exploits the avenue provided by the neoplastic microvasculature to deliver high-energy, low-penetrating therapeutic doses of radiation. Variant hepatic arterial anatomy, collateral vessels, and changes in flow dynamics during treatment can affect particle dispersion and lead to nontarget particle distribution and subsequent gastrointestinal morbidity. Awareness of these variances and techniques to prevent gastrointestinal tract microsphere delivery is essential in mitigating this serious complication. Our aim is to increase the understanding of the role of various imaging and preventative techniques in minimizing this undesired effect.
UR - http://www.scopus.com/inward/record.url?scp=34147190131&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=34147190131&partnerID=8YFLogxK
U2 - 10.1016/j.jvir.2007.02.002
DO - 10.1016/j.jvir.2007.02.002
M3 - Article
C2 - 17446547
AN - SCOPUS:34147190131
VL - 18
SP - 553
EP - 561
JO - Journal of Vascular and Interventional Radiology
JF - Journal of Vascular and Interventional Radiology
SN - 1051-0443
IS - 4
ER -