Gastrointestinal mast cells: New approaches for analyzing their function in vivo

B. K. Wershil, S. J. Galli

Research output: Contribution to journalReview articlepeer-review

17 Scopus citations

Abstract

Mast cells have been implicated in a variety of physiologic or pathologic responses in the gastrointestinal tract; however, the precise contributions of the mast cell to these reactions have been difficult to define. This article discusses general aspects of mast cell biology, outlines new approaches for the analysis of mast cell function in vivo, and reviews recent evidence indicating that mast cells can produce a wide spectrum of multifunctional cytokines.

Original languageEnglish (US)
Pages (from-to)613-627
Number of pages15
JournalGastroenterology Clinics of North America
Volume20
Issue number3
StatePublished - 1991

ASJC Scopus subject areas

  • Gastroenterology

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