Abstract
A Gd(III)-nanodiamond conjugate [Gd(III)-ND] was prepared and characterized, enabling detection of nanodiamonds by MR imaging. The Gd(III)-ND particles significantly reduced the T1 of water protons with a per-Gd(III) relaxlvity of 58.82 ± 1.18 mM-1 s-1 at 1.5 T (60 MHz). This represents a 10-fold increase compared to the monomer Gd(III) complex (r1= 5.42 ± 0.20 mM-1 s -1) and is among the highest per-Gd(III) relaxivities reported.
Original language | English (US) |
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Pages (from-to) | 484-489 |
Number of pages | 6 |
Journal | Nano letters |
Volume | 10 |
Issue number | 2 |
DOIs | |
State | Published - Feb 10 2010 |
Keywords
- Gadolinium
- MR contrast agents
- Nanodiamonds
- Nanomedicine
ASJC Scopus subject areas
- Bioengineering
- Chemistry(all)
- Materials Science(all)
- Condensed Matter Physics
- Mechanical Engineering