Gene expression of TMEM178, which encodes a negative regulator of NFATc1, decreases with the progression of asthma severity

Naiya B. Patel, Lorena A. Ostilla, Lyda Cuervo-Pardo, Sergejs Berdnikovs, Sergio E. Chiarella*

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

Abstract

In two independent microarray studies involving primary airway epithelial cells, the relative gene expression of TMEM178 decreases with the progression of asthma severity. Our manuscript creates a paradigm for future studies dissecting the role of Tmem178 in the pathogenesis of severe asthma.

Original languageEnglish (US)
Article number38
JournalClinical and Translational Allergy
Volume9
Issue number1
DOIs
StatePublished - Aug 8 2019

Keywords

  • Airway epithelium
  • Asthma
  • Inflammation
  • Microarray

ASJC Scopus subject areas

  • Immunology and Allergy
  • Immunology
  • Pulmonary and Respiratory Medicine

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