Gene expression profiling of renal cell carcinoma

Min Han Tan, Craig G. Rogers, Jeffrey T. Cooper, Jonathon A. Ditlev, Thomas J. Maatman, Ximing Yang, Kyle A. Furge, Bin Tean Teh*, Robert Figlin, Michael Atkins, James Yang

*Corresponding author for this work

Research output: Contribution to journalArticle

35 Scopus citations

Abstract

Renal cell carcinoma (RCC) is a histologically diverse disease, with variable and often unpredictable clinical behavior. The prognosis worsens dramatically with the onset of clinical metastasis, and current regimens of systemic therapy yield only modest benefits for metastatic RCC. Gene expression profiling is a promising technique for refining the diagnosis and staging of RCC, as well as for highlighting potential therapeutic targets. We review the recent advances in expression profiling of RCC and discuss the clinical and biological insights obtained from these studies.

Original languageEnglish (US)
Pages (from-to)6315s-6321s
JournalClinical Cancer Research
Volume10
Issue number18 II
DOIs
StatePublished - Sep 15 2004

ASJC Scopus subject areas

  • Oncology
  • Cancer Research

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    Tan, M. H., Rogers, C. G., Cooper, J. T., Ditlev, J. A., Maatman, T. J., Yang, X., Furge, K. A., Teh, B. T., Figlin, R., Atkins, M., & Yang, J. (2004). Gene expression profiling of renal cell carcinoma. Clinical Cancer Research, 10(18 II), 6315s-6321s. https://doi.org/10.1158/1078-0432.CCR-050002