Gene expression profiling of renal cell carcinoma and its implications in diagnosis, prognosis, and therapeutics

Masayuki Takahashi*, Jun Sugimura, Ximing Yang, Nicholas Vogelzang, Bin S. Teh, Kyle Furge, Bin T. Teh

*Corresponding author for this work

Research output: Contribution to journalArticle

28 Scopus citations

Abstract

Renal cell carcinoma (RCC) is the 10th most common cancer in the United States. It is a histologically heterogeneous disease with various histologic types being characterized by distinct genetic alterations. This chapter reviews advances in the gene expression profiling of RCC and discusses their clinical implications. Data are promising, and many more RCC-related microarray studies are currently underway or in planning. Undoubtedly these data will have an impact on the diagnosis, prognosis, and treatment of RCCs in the future. Finally, this chapter discusses what additional studies should be performed to help uncover the molecular mechanisms of RCC and to bring this new knowledge into use in the clinical arena.

Original languageEnglish (US)
Pages (from-to)157-181
Number of pages25
JournalAdvances in Cancer Research
Volume89
DOIs
StatePublished - Jan 1 2003

ASJC Scopus subject areas

  • Oncology
  • Cancer Research

Fingerprint Dive into the research topics of 'Gene expression profiling of renal cell carcinoma and its implications in diagnosis, prognosis, and therapeutics'. Together they form a unique fingerprint.

  • Cite this