Gene therapy for atrial fibrillation - How close to clinical implementation?

Amar Trivedi, Jacob Hoffman, Rishi Arora*

*Corresponding author for this work

Research output: Contribution to journalReview article

3 Scopus citations

Abstract

In this review we examine the current state of gene therapy for the treatment of cardiac arrhythmias. We describe advances and challenges in successfully creating and incorporating gene vectors into the myocardium. After summarizing the current scientific research in gene transfer technology we then focus on the most promising areas of gene therapy, the treatment of atrial fibrillation and ventricular tachyarrhythmias. We review the scientific literature to determine how gene therapy could potentially be used to treat patients with cardiac arrhythmias.

Original languageEnglish (US)
Pages (from-to)177-183
Number of pages7
JournalInternational Journal of Cardiology
Volume296
DOIs
StatePublished - Dec 1 2019

Keywords

  • Atrial fibrillation
  • Gene therapy
  • Genomic therapy
  • Ventricular tachycardia

ASJC Scopus subject areas

  • Cardiology and Cardiovascular Medicine

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