General Principles and Pharmacology of Biologics in Inflammatory Bowel Disease

Patricia L. Kozuch, Stephen B. Hanauer*

*Corresponding author for this work

Research output: Contribution to journalReview articlepeer-review

33 Scopus citations

Abstract

The pharmacology of each biologic agent is important regarding the dose required to achieve benefits, duration of therapeutic effect, and the induction of immunogenicity. Comprehension of the individual pharmacology, pharmacodynamics, and pharmacokinetics, in addition to the impact of concomitant immunomodulation on immunogenicity allows optimization of each biologic agent in the appropriate inductive or maintenance setting of IBD.

Original languageEnglish (US)
Pages (from-to)757-773
Number of pages17
JournalGastroenterology Clinics of North America
Volume35
Issue number4
DOIs
StatePublished - Dec 2006

ASJC Scopus subject areas

  • Gastroenterology

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