General Principles and Pharmacology of Biologics in Inflammatory Bowel Disease

Patricia L. Kozuch; Stephen B. Hanauer

doi:10.1016/j.gtc.2006.09.005

General Principles and Pharmacology of Biologics in Inflammatory Bowel Disease

Patricia L. Kozuch, Stephen B. Hanauer^*

^*Corresponding author for this work

Medicine, Gastroenterology Division

Research output: Contribution to journal › Review article › peer-review

33 Scopus citations

Abstract

The pharmacology of each biologic agent is important regarding the dose required to achieve benefits, duration of therapeutic effect, and the induction of immunogenicity. Comprehension of the individual pharmacology, pharmacodynamics, and pharmacokinetics, in addition to the impact of concomitant immunomodulation on immunogenicity allows optimization of each biologic agent in the appropriate inductive or maintenance setting of IBD.

Original language	English (US)
Pages (from-to)	757-773
Number of pages	17
Journal	Gastroenterology Clinics of North America
Volume	35
Issue number	4
DOIs	https://doi.org/10.1016/j.gtc.2006.09.005
State	Published - Dec 2006

ASJC Scopus subject areas

Gastroenterology

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General Principles and Pharmacology of Biologics in Inflammatory Bowel Disease

Abstract

ASJC Scopus subject areas

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