Abstract
The pharmacology of each biologic agent is important regarding the dose required to achieve benefits, duration of therapeutic effect, and the induction of immunogenicity. Comprehension of the individual pharmacology, pharmacodynamics, and pharmacokinetics, in addition to the impact of concomitant immunomodulation on immunogenicity allows optimization of each biologic agent in the appropriate inductive or maintenance setting of IBD.
Original language | English (US) |
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Pages (from-to) | 757-773 |
Number of pages | 17 |
Journal | Gastroenterology Clinics of North America |
Volume | 35 |
Issue number | 4 |
DOIs | |
State | Published - Dec 2006 |
ASJC Scopus subject areas
- Gastroenterology