Abstract
To the Editor: Conneally has presented an informative discussion of the implications of the detection of markers for a major gene (May 16 issue).1 The immediate stimulus was the report by Siddique et al. in the same issue of four DNA markers on the long arm of chromosome 4 that, in a subgroup of families, were linked to the familial form of amyotrophic lateral sclerosis.2 In sharing with us some of the background of the study, Conneally points out that a simple but highly unusual step was critical to its success — the decision by two competing groups of investigators.
Original language | English (US) |
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Pages (from-to) | 1382-1383 |
Number of pages | 2 |
Journal | New England Journal of Medicine |
Volume | 325 |
Issue number | 19 |
DOIs | |
State | Published - Nov 7 1991 |
ASJC Scopus subject areas
- Medicine(all)