Genetic control of biogenic-amine systems in Drosophila under normal and stress conditions

Akinori Hirashima*, Madina Jh Sukhanova, Inga Yu Rauschenbach

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

20 Scopus citations

Abstract

The contents of octopamine and its precursors (tyrosine and tyramine) were studied in adults of two lines of Drosophila virilis with contrasting stress responses. It was demonstrated that in individuals responding to stress by a hormonal stress reaction (line 101), the contents of octopamine and tyrosine are lower than in nonresponding flies (line 147). It was found that there is no difference between the lines in the level of tyramine under normal conditions. The dopamine response to stressor was also studied. Genetic analysis of these differences revealed that they are controlled by a single gene and that the gene is not sex-linked. The gene controlling the response was found to be linked to chromosome 6 of D. virilis.

Original languageEnglish (US)
Pages (from-to)167-180
Number of pages14
JournalBiochemical Genetics
Volume38
Issue number5-6
StatePublished - Nov 16 2000
Externally publishedYes

Keywords

  • Dopamine
  • Drosophila virilis
  • Octopamine
  • Tyramine
  • Tyrosine

ASJC Scopus subject areas

  • Ecology, Evolution, Behavior and Systematics
  • Biochemistry
  • Molecular Biology
  • Genetics

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