Genetic Identification of Vagal Sensory Neurons That Control Feeding

Ling Bai, Sheyda Mesgarzadeh, Karthik S. Ramesh, Erica L. Huey, Yin Liu, Lindsay A. Gray, Tara J. Aitken, Yiming Chen, Lisa R. Beutler, Jamie S. Ahn, Linda Madisen, Hongkui Zeng, Mark A. Krasnow, Zachary A. Knight*

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

224 Scopus citations


A single-cell approach cataloging the sensory neurons in the vagus nerve identifies populations that suppress hunger through mechanosensation in the intestine.

Original languageEnglish (US)
Pages (from-to)1129-1143.e23
Issue number5
StatePublished - Nov 14 2019


  • AgRP Neurons
  • RNA sequencing
  • chemogenetics
  • fiber photometry
  • hypothalamus
  • optogenetics
  • satiation
  • stretch
  • vagal afferents
  • vagus nerve

ASJC Scopus subject areas

  • General Biochemistry, Genetics and Molecular Biology


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