Genetic Identification of Vagal Sensory Neurons That Control Feeding

Ling Bai, Sheyda Mesgarzadeh, Karthik S. Ramesh, Erica L. Huey, Yin Liu, Lindsay A. Gray, Tara J. Aitken, Yiming Chen, Lisa R. Beutler, Jamie S. Ahn, Linda Madisen, Hongkui Zeng, Mark A. Krasnow, Zachary A. Knight*

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

40 Scopus citations

Abstract

A single-cell approach cataloging the sensory neurons in the vagus nerve identifies populations that suppress hunger through mechanosensation in the intestine.

Original languageEnglish (US)
Pages (from-to)1129-1143.e23
JournalCell
Volume179
Issue number5
DOIs
StatePublished - Nov 14 2019

Keywords

  • AgRP Neurons
  • RNA sequencing
  • chemogenetics
  • fiber photometry
  • hypothalamus
  • optogenetics
  • satiation
  • stretch
  • vagal afferents
  • vagus nerve

ASJC Scopus subject areas

  • Biochemistry, Genetics and Molecular Biology(all)

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