Abstract
Klebsiella pneumoniae is a nosocomial pathogen of emerging importance and displays resistance to broad-spectrum antibiotics, such as carbapenems. Here, we report the genome sequences of five clinical K. pneumoniae isolates, four of which are carbapenem resistant. Carbapenem resistance is conferred by hydrolyzing class A β-lactamases found adjacent to transposases.
| Original language | English (US) |
|---|---|
| Article number | e00040-16 |
| Journal | Genome Announcements |
| Volume | 4 |
| Issue number | 2 |
| DOIs | |
| State | Published - 2016 |
Funding
The project was supported partly by a CONNECT program grant award from UTSA (J.S.). This work received computational support from the Computational System Biology Core and sequencing support from the Genomics Core, funded by the National Institute on Minority Health and Health Disparities (G12MD007591) from the National Institutes of Health. The study was further supported in part by the U.S. Department of Homeland Security under contract 2014-ST-062-000058, the Department of Biology, and South Texas Center for Emerging Infectious Diseases (STCEID) at the University of Texas at San Antonio. B.R. is supported in part by the Swiss National Science Foundation Early Postdoc Mobility Fellowship (P2LAP3-151770).
ASJC Scopus subject areas
- Molecular Biology
- Genetics
