Genome-wide RNA interference screen identifies previously undescribed regulators of polyglutamine aggregation

Keyphrases

• Protein Misfolding 100%
• Protein Aggregates 100%
• RNA Interference Screen 100%
• Polyglutamine Aggregation 100%
• Protein Folding 100%
• Polyglutamine Expansion 100%
• Neurodegenerative Diseases 50%
• Protein Factor 50%
• Homeostasis 50%
• Regulatory Genes 50%
• Fusion Protein 50%
• Protein Degradation 50%
• Protein Aggregation 50%
• RNA Interference 50%
• Protein Synthesis 50%
• Molecular Machines 50%
• Age-related Changes 50%
• Age-dependent 50%
• Misfolding 50%
• Polyglutamine 50%
• Damaged Proteins 50%
• Protein Trafficking 50%
• Polyglutamine Disease 50%
• RNA Metabolism 50%
• Human Genetic Disease 50%
• Yellow Fluorescent Protein 50%
• Fluorescent Protein Fusions 50%
• Transgenic Caenorhabditis Elegans 50%

Biochemistry, Genetics and Molecular Biology

• Protein Misfolding 100%
• Protein Folding 100%
• RNAI 100%
• Protein Catabolism 50%
• Protein Aggregation 50%
• Locus Control Region 50%
• Genetic Disorder 50%
• Human Genetics 50%
• Protein Biosynthesis 50%
• Transgenics 50%
• Homeostasis 50%
• Caenorhabditis Elegans 50%
• Protein Targeting 50%
• RNA Metabolism 50%
• Yellow Fluorescent Protein 50%
• Chimeric Protein 50%

Neuroscience

• Polyglutamine 100%
• RNAI 100%
• Protein Folding 40%
• Protein Misfolding 40%
• Protein Aggregate 40%
• Protein Targeting 20%
• Protein Biosynthesis 20%
• Molecular Machines 20%
• Neurodegenerative Disorder 20%
• Protein Aggregation 20%
• Regulator Gene 20%
• Chimeric Protein 20%
• Yellow Fluorescent Protein 20%
• RNA Metabolism 20%
• Caenorhabditis Elegans 20%