Geographic variation in the management and outcome of patients with AIDS-related Pneumocystis carinii pneumonia

Susan E. Cohn*, Jonathan D. Klein, Robert A. Weinstein, Martin F. Shapiro, Jack A. DeHovitz, Harold A. Kessler, Gordon M. Dickinson, Daniel C. Rodrigue, Charles L. Bennett

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

11 Scopus citations


Pneumocystis carinii pneumonia (PCP) is one of the most common reasons for the hospitalization of AIDS patients; however, geographic differences in PCP management have not been evaluated previously. Therefore, we abstracted data on socioeconomic characteristics, prior HIV care, severity of illness, timeliness and intensity of in-hospital care, duration of hospitalization, and survival from 1547 randomly selected medical records of patients hospitalized with AIDS-related PCP between 1987 and 1990 at 82 hospitals in Chicago, Los Angeles, Miami, New York City, and Raleigh-Durham, North Carolina. Multivariate regression models were used to assess factors associated with longer hospital stays and increased inpatient mortality. Our results showed that in-hospital mortality ranged from 15% to 27%, bronchoscopy rates from 53% to 70%, and mean length of stay from 14 days to 23 days. Geographic variations in mortality were accounted for by differences in severity of illness at admission, insurance status, and in-hospital patient management. However, significant regional variations in hospital length of stay persisted, even after adjusting for patient demographics, severity of illness, and use of diagnostic and therapeutic care resources.

Original languageEnglish (US)
Pages (from-to)408-415
Number of pages8
JournalJournal of Acquired Immune Deficiency Syndromes and Human Retrovirology
Issue number5
StatePublished - 1996


  • AIDS
  • Mortality
  • Physician practice patterns
  • Pneumocystis carinii pneumonia
  • Regional variation

ASJC Scopus subject areas

  • Virology
  • Immunology and Allergy
  • Immunology


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