Germ Cell Tumors of the Ovary

Daniela E. Matei; A. Lindsay Frazier; Jean A. Hurteau; Farzana D. Pashankar

doi:10.1002/9781119196235.ch35

Germ Cell Tumors of the Ovary

Daniela E. Matei, A. Lindsay Frazier, Jean A. Hurteau, Farzana D. Pashankar

Medicine, Hematology Oncology Division

Research output: Chapter in Book/Report/Conference proceeding › Chapter

Abstract

Ovarian germ cell tumors (GCTs) are rare tumors affecting predominantly girls or young women. Primitive GCTs comprise dysgerminomas and nondysgerminomatous GCT, which include yolk sac tumor, embryonal carcinoma, polyembryoma, nongestational choriocarcinoma, and mixed GCTs. Principles of diagnosis and treatment apply across all histological types. Cisplatin-based chemotherapy represents the cornerstone of treatment. With the available current multidisciplinary approach, most women with ovarian GCTs are cured. Given the long life expectancy of survivors, current efforts are concentrated on minimizing long-term toxicities, preserving fertility, and quality of life.

Original language	English (US)
Title of host publication	Textbook of Uncommon Cancer
Subtitle of host publication	Fifth Edition
Publisher	wiley
Pages	518-532
Number of pages	15
ISBN (Electronic)	9781119196235
ISBN (Print)	9781119196204
DOIs	https://doi.org/10.1002/9781119196235.ch35
State	Published - Jan 1 2017

ASJC Scopus subject areas

General Medicine

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

Access to Document

10.1002/9781119196235.ch35

Cite this

@inbook{fdaffc1990b04446a87f8fa49d125cfc,

title = "Germ Cell Tumors of the Ovary",

abstract = "Ovarian germ cell tumors (GCTs) are rare tumors affecting predominantly girls or young women. Primitive GCTs comprise dysgerminomas and nondysgerminomatous GCT, which include yolk sac tumor, embryonal carcinoma, polyembryoma, nongestational choriocarcinoma, and mixed GCTs. Principles of diagnosis and treatment apply across all histological types. Cisplatin-based chemotherapy represents the cornerstone of treatment. With the available current multidisciplinary approach, most women with ovarian GCTs are cured. Given the long life expectancy of survivors, current efforts are concentrated on minimizing long-term toxicities, preserving fertility, and quality of life.",

author = "Matei, {Daniela E.} and Frazier, {A. Lindsay} and Hurteau, {Jean A.} and Pashankar, {Farzana D.}",

note = "Publisher Copyright: {\textcopyright} 2017 John Wiley & Sons Ltd.",

year = "2017",

month = jan,

day = "1",

doi = "10.1002/9781119196235.ch35",

language = "English (US)",

isbn = "9781119196204",

pages = "518--532",

booktitle = "Textbook of Uncommon Cancer",

publisher = "wiley",

}

TY - CHAP

T1 - Germ Cell Tumors of the Ovary

AU - Matei, Daniela E.

AU - Frazier, A. Lindsay

AU - Hurteau, Jean A.

AU - Pashankar, Farzana D.

PY - 2017/1/1

Y1 - 2017/1/1

N2 - Ovarian germ cell tumors (GCTs) are rare tumors affecting predominantly girls or young women. Primitive GCTs comprise dysgerminomas and nondysgerminomatous GCT, which include yolk sac tumor, embryonal carcinoma, polyembryoma, nongestational choriocarcinoma, and mixed GCTs. Principles of diagnosis and treatment apply across all histological types. Cisplatin-based chemotherapy represents the cornerstone of treatment. With the available current multidisciplinary approach, most women with ovarian GCTs are cured. Given the long life expectancy of survivors, current efforts are concentrated on minimizing long-term toxicities, preserving fertility, and quality of life.

AB - Ovarian germ cell tumors (GCTs) are rare tumors affecting predominantly girls or young women. Primitive GCTs comprise dysgerminomas and nondysgerminomatous GCT, which include yolk sac tumor, embryonal carcinoma, polyembryoma, nongestational choriocarcinoma, and mixed GCTs. Principles of diagnosis and treatment apply across all histological types. Cisplatin-based chemotherapy represents the cornerstone of treatment. With the available current multidisciplinary approach, most women with ovarian GCTs are cured. Given the long life expectancy of survivors, current efforts are concentrated on minimizing long-term toxicities, preserving fertility, and quality of life.

UR - http://www.scopus.com/inward/record.url?scp=85211860857&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=85211860857&partnerID=8YFLogxK

U2 - 10.1002/9781119196235.ch35

DO - 10.1002/9781119196235.ch35

M3 - Chapter

AN - SCOPUS:85211860857

SN - 9781119196204

SP - 518

EP - 532

BT - Textbook of Uncommon Cancer

PB - wiley

ER -

Germ Cell Tumors of the Ovary

Abstract

ASJC Scopus subject areas

UN SDGs

Access to Document

Other files and links

Fingerprint

Cite this