Gestational Diabetes Mellitus

Emily D. Szmuilowicz, Jami L. Josefson, Boyd E. Metzger*

*Corresponding author for this work

Research output: Contribution to journalReview articlepeer-review

39 Scopus citations

Abstract

Although it has been accepted for decades that women with gestational diabetes mellitus (GDM) are at high risk for future development of type 2 diabetes, vigorous debate regarding the value of detecting and treating GDM has persisted into the twenty-first century. Although results from 2 randomized trials provide strong evidence that treating GDM reduces adverse perinatal outcomes, it remains to be determined whether treatment impacts long-term offspring outcomes. Insulin is the first-line pharmacologic treatment and is added when glycemic goals are not met with nutritional modifications. Oral agent use is controversial, as data on long-term offspring outcomes are lacking.

Original languageEnglish (US)
Pages (from-to)479-493
Number of pages15
JournalEndocrinology and Metabolism Clinics of North America
Volume48
Issue number3
DOIs
StatePublished - Sep 2019

Keywords

  • Diagnosis
  • Gestational diabetes mellitus
  • Offspring
  • Outcomes
  • Pregnancy
  • Treatment

ASJC Scopus subject areas

  • Endocrinology, Diabetes and Metabolism
  • Endocrinology

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