Gestational trophoblastic disease I: Epidemiology, pathology, clinical presentation and diagnosis of gestational trophoblastic disease, and management of hydatidiform mole

John R. Lurain*

*Corresponding author for this work

Research output: Contribution to journalReview articlepeer-review

329 Scopus citations

Abstract

Gestational trophoblastic disease includes hydatidiform mole (complete and partial) and gestational trophoblastic neoplasia (invasive mole, choriocarcinoma, placental site trophoblastic tumor, and epithelioid trophoblastic tumor). The epidemiology, pathology, clinical presentation, and diagnosis of each of these trophoblastic disease variants are discussed. Particular emphasis is given to management of hydatidiform mole, including evacuation, twin mole/normal fetus pregnancy, prophylactic chemotherapy, and follow-up.

Original languageEnglish (US)
Pages (from-to)531-539
Number of pages9
JournalAmerican journal of obstetrics and gynecology
Volume203
Issue number6
DOIs
StatePublished - Dec 2010

Keywords

  • Chemotherapy
  • Choriocarcinoma
  • Gestational trophoblastic disease
  • Gestational trophoblastic neoplasia
  • Hydatidiform mole

ASJC Scopus subject areas

  • Obstetrics and Gynecology

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