Giant Actinomyces brain abscess in an immunocompetent child: A management strategy

Nicole H.Nchicoine Chicoine, Jackson Griffith-Linsley, Joling Goh, John J. Manaloor, Jeffrey S. Raskin*

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review


Background: Intraparenchymal brain abscess is a collection of microbes caused by inoculation through direct extension or hematogenous spread. Although rare, intraparenchymal abscesses are potentially fatal and can be detected when patients are symptomatic due to local mass effect on adjacent neural tissue. Brain abscess treatment includes medical management with appropriate antibiotics alone or medical management in combination with surgical debridement. Treatment strategies depend on the size and location of disease, as well as the virulence of the microorganism. Similar to medical management strategies, surgical strategies among providers are not uniform, with variation in approaches from complete extirpation of the abscess, including the abscess wall, to minimally invasive stereotactic needle aspiration. In particular, for children, there are no guidelines for therapy. Case Description: We report a case of giant Actinomycosis right frontal brain abscess in an immunocompetent child without risk factors. A review of the literature for the treatment of brain abscess caused very rarely by Actinomyces in children is performed. Conclusion: Successful treatment of brain access depends on organism and location. The even more uncommon giant intraparenchymal abscesses can be managed with minimal access and prolonged antibiosis, especially when slow-growing organisms are identified. Long-Term follow-up should be employed to mitigate missed late failures.

Original languageEnglish (US)
Article number325
JournalSurgical Neurology International
StatePublished - 2021


  • Actinomyces
  • Brain abscess
  • Medical management
  • Surgical

ASJC Scopus subject areas

  • Clinical Neurology
  • Surgery


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