Giant hepatic adenoma with atypical features in a patient on oxcarbazepine therapy

T. B. Lautz, M. J. Finegold, A. C. Chin, R. A. Superina*

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

14 Scopus citations

Abstract

An association between oxcarbazepine therapy and hepatic adenoma (HA) has been documented in animal models but not observed in humans. The authors report a case of a 16-year-old girl on oxcarbazepine therapy for seizure disorder who presented with a giant HA. Pathology of the HA was notable for marked periductal fibrosis and glycoprotein inclusions in the nontumor liver. The patient was not on oral contraceptives and has no other known risk factors for HA.

Original languageEnglish (US)
Pages (from-to)751-754
Number of pages4
JournalJournal of pediatric surgery
Volume43
Issue number4
DOIs
StatePublished - Apr 2008

Keywords

  • Antiepileptic medication
  • Seizure
  • Surgery

ASJC Scopus subject areas

  • Surgery
  • Pediatrics, Perinatology, and Child Health

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