TY - JOUR
T1 - Gingival hyperplasia
T2 - a side effect of nifedipine and diltiazem
AU - Fattore, La Deane
AU - Stablein, Michael
AU - Bredfeldt, Glen
AU - Semla, Todd
AU - Moran, Maureen
AU - Doherty‐Greenberg, Jean Marie
PY - 1991/5
Y1 - 1991/5
N2 - Currently, calcium channel blockers are being used increasingly for the treatment of hypertension in the elderly. Several case reports in the dental literature suggest that patients treated with the calcium channel blockers manifest gingival hyperplasia similar to that seen in patients taking phenytoin (Dilantin, Parke‐Davis). A small study of 89 patients undertaken at the Westside Veterans Administration Medical Center, Chicago seems to indicate that nifedipine and diltiazem do indeed cause gingival hyperplasia. A total of 83% of the patients studied receiving nifedipine showed evidence of hyperplastic tissue and 74% of those on diltiazem were found to have hyperplastic tissue
AB - Currently, calcium channel blockers are being used increasingly for the treatment of hypertension in the elderly. Several case reports in the dental literature suggest that patients treated with the calcium channel blockers manifest gingival hyperplasia similar to that seen in patients taking phenytoin (Dilantin, Parke‐Davis). A small study of 89 patients undertaken at the Westside Veterans Administration Medical Center, Chicago seems to indicate that nifedipine and diltiazem do indeed cause gingival hyperplasia. A total of 83% of the patients studied receiving nifedipine showed evidence of hyperplastic tissue and 74% of those on diltiazem were found to have hyperplastic tissue
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U2 - 10.1111/j.1754-4505.1991.tb00828.x
DO - 10.1111/j.1754-4505.1991.tb00828.x
M3 - Article
C2 - 1887359
AN - SCOPUS:0026163682
SN - 0275-1879
VL - 11
SP - 107
EP - 109
JO - Special Care in Dentistry
JF - Special Care in Dentistry
IS - 3
ER -