Gliome - Was ich wissen muss in zehn Fragen

Translated title of the contribution: Gliomas - What i Have to Know in ten Questions

Wiebke Gulden-Sala, Patrick Roth, Michelle Brown, Nicolaus Andratschke, Michael Weller, Roger Stupp

Research output: Contribution to journalReview article

Abstract

Gliomas are the most common primary tumors involving the central nervous system. They can manifest with diverse and non-specifi c general and neurological symptoms. The diagnostic gold standard is cerebral magnetic resonance imaging and subsequent histological confi rmation of the diagnosis. Steroids, especially dexamethasone, are used in case of focal symptoms and of symptoms caused by increased intracranial pressure, and antiepileptic drugs are used to manage epileptic seizures. Non-enzyme-inducing antiepileptic drugs are preferable. Glioma patients have an inherently elevated thromboembolic risk, and therapeutic anticoagulation is indicated following a thromboembolic event. Surgery, radiotherapy and systemic therapy are used as tumor-specifi c therapy modalities in gliomas. Molecular markers play an increasing role in the prognosis and selection of therapy in daily oncological routine.

Original languageGerman
Pages (from-to)330-337
Number of pages8
JournalPraxis
Volume105
Issue number6
DOIs
StatePublished - Mar 2016

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Keywords

  • Antiepileptics
  • Glioblastoma
  • Oligodendroglioma
  • Steroids
  • Thrombosis

ASJC Scopus subject areas

  • Medicine(all)

Cite this

Gulden-Sala, W., Roth, P., Brown, M., Andratschke, N., Weller, M., & Stupp, R. (2016). Gliome - Was ich wissen muss in zehn Fragen. Praxis, 105(6), 330-337. https://doi.org/10.1024/1661-8157/a002303