Abstract
Viral infection causes the host to activate an antiviral response that, in part, is dependent on mitochondrial antiviral signaling protein (MAVS) to stimulate type I interferons. Zhang et al. (2019) demonstrate that glucose-generated lactate interacts with MAVS to suppress type I interferons. This study links glucose metabolism to antiviral responses. Viral infection causes the host to activate an antiviral response that, in part, is dependent on mitochondrial antiviral signaling protein (MAVS) to stimulate type I interferons. Zhang et al. (2019) demonstrate that glucose-generated lactate interacts with MAVS to suppress type I interferons. This study links glucose metabolism to antiviral responses.
Original language | English (US) |
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Pages (from-to) | 10-11 |
Number of pages | 2 |
Journal | Cell |
Volume | 178 |
Issue number | 1 |
DOIs | |
State | Published - Jun 27 2019 |
ASJC Scopus subject areas
- General Biochemistry, Genetics and Molecular Biology