Glycogen‐rich clear cell carcinoma of the breast: Report of a case with fine‐needle aspiration cytology and immunocytochemical and ultrastructural studies

Borislav A. Alexiev*

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

11 Scopus citations

Abstract

Fine‐needle aspiration cytology, immunocytochemistry, and electron microscopic findings are described in a case of glycogen‐rich clear cell carcinoma of the breast. the aspirate contained many small and large papillary cell groups and numerous single tall columnar cells with apical cytoplasmic projections and mild to moderate degree of nuclear pleomorphism. Cytochemical localisation of glycogen and immunostaining on air‐dried smears with CEA and actin monoclonal antibodies permitted the correct identification and differential diagnosis of the tumor. Electron microscopic examination of the resected specimen confirmed the diagnosis of glycogen‐rich clear cell carcinoma. the differential diagnosis and potential diagnostic pitfalls are discussed, and recommendation are offered to prevent misdiagnosis.

Original languageEnglish (US)
Pages (from-to)62-66
Number of pages5
JournalDiagnostic Cytopathology
Volume12
Issue number1
DOIs
StatePublished - Jan 1 1995

Keywords

  • Breast
  • Fine‐needle aspiration cytology
  • Glycogen‐rich carcinoma
  • Immunocytochemistry

ASJC Scopus subject areas

  • Pathology and Forensic Medicine
  • Histology

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