Gold Nanoparticle-Based Biodetection for Chip-Based Portable Diagnosis Systems

Shifeng Li; Edgar Goluch; Chang Liu; Sandra Szegedi; Kashan Shaikh; Faysal Ahmed; Alan Hu; Shenshen Zhao

doi:10.1016/j.jala.2009.11.001

Gold Nanoparticle-Based Biodetection for Chip-Based Portable Diagnosis Systems

Shifeng Li, Edgar Goluch, Chang Liu^*, Sandra Szegedi, Kashan Shaikh, Faysal Ahmed, Alan Hu, Shenshen Zhao

^*Corresponding author for this work

Mechanical Engineering

Research output: Contribution to journal › Article › peer-review

6 Scopus citations

Abstract

We review the past development of highly sensitive and selective gold nanoparticle (AuNP)-based assays of protein and DNA biomarkers for chip-based detection systems. The microfluidic systems, various assays, and preliminary laboratory results are shown. AuNP-based biodetection assays provide low detection threshold, offering promises for multiplexed diagnostics of many forms of disease markers.

Original language	English (US)
Pages (from-to)	107-113
Number of pages	7
Journal	JALA - Journal of the Association for Laboratory Automation
Volume	15
Issue number	2
DOIs	https://doi.org/10.1016/j.jala.2009.11.001
State	Published - Apr 2010

Keywords

biobarcode
gold nanoparticles
lab-on-chip

ASJC Scopus subject areas

Computer Science Applications
Medical Laboratory Technology

Access to Document

10.1016/j.jala.2009.11.001

Cite this

@article{5fe40715d23d4bb5aa8992862e31b941,

title = "Gold Nanoparticle-Based Biodetection for Chip-Based Portable Diagnosis Systems",

abstract = "We review the past development of highly sensitive and selective gold nanoparticle (AuNP)-based assays of protein and DNA biomarkers for chip-based detection systems. The microfluidic systems, various assays, and preliminary laboratory results are shown. AuNP-based biodetection assays provide low detection threshold, offering promises for multiplexed diagnostics of many forms of disease markers.",

keywords = "biobarcode, gold nanoparticles, lab-on-chip",

author = "Shifeng Li and Edgar Goluch and Chang Liu and Sandra Szegedi and Kashan Shaikh and Faysal Ahmed and Alan Hu and Shenshen Zhao",

note = "Funding Information: Work discussed in this review has been supported by the United States National Science Foundation (Nanoscale Science and Engineering Center), The Department of Defense (DARPA Symbiotic Project) , and the National Institutes of Health (NIH Center for Excellence in Cancer Nanotechnology) . Copyright: Copyright 2010 Elsevier B.V., All rights reserved.",

year = "2010",

month = apr,

doi = "10.1016/j.jala.2009.11.001",

language = "English (US)",

volume = "15",

pages = "107--113",

journal = "JALA - Journal of the Association for Laboratory Automation",

issn = "1535-5535",

publisher = "Association for Laboratory Automation",

number = "2",

}

TY - JOUR

T1 - Gold Nanoparticle-Based Biodetection for Chip-Based Portable Diagnosis Systems

AU - Li, Shifeng

AU - Goluch, Edgar

AU - Liu, Chang

AU - Szegedi, Sandra

AU - Shaikh, Kashan

AU - Ahmed, Faysal

AU - Hu, Alan

AU - Zhao, Shenshen

N1 - Funding Information: Work discussed in this review has been supported by the United States National Science Foundation (Nanoscale Science and Engineering Center), The Department of Defense (DARPA Symbiotic Project) , and the National Institutes of Health (NIH Center for Excellence in Cancer Nanotechnology) . Copyright: Copyright 2010 Elsevier B.V., All rights reserved.

PY - 2010/4

Y1 - 2010/4

N2 - We review the past development of highly sensitive and selective gold nanoparticle (AuNP)-based assays of protein and DNA biomarkers for chip-based detection systems. The microfluidic systems, various assays, and preliminary laboratory results are shown. AuNP-based biodetection assays provide low detection threshold, offering promises for multiplexed diagnostics of many forms of disease markers.

AB - We review the past development of highly sensitive and selective gold nanoparticle (AuNP)-based assays of protein and DNA biomarkers for chip-based detection systems. The microfluidic systems, various assays, and preliminary laboratory results are shown. AuNP-based biodetection assays provide low detection threshold, offering promises for multiplexed diagnostics of many forms of disease markers.

KW - biobarcode

KW - gold nanoparticles

KW - lab-on-chip

UR - http://www.scopus.com/inward/record.url?scp=77649327204&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=77649327204&partnerID=8YFLogxK

U2 - 10.1016/j.jala.2009.11.001

DO - 10.1016/j.jala.2009.11.001

M3 - Article

AN - SCOPUS:77649327204

SN - 1535-5535

VL - 15

SP - 107

EP - 113

JO - JALA - Journal of the Association for Laboratory Automation

JF - JALA - Journal of the Association for Laboratory Automation

IS - 2

ER -

Gold Nanoparticle-Based Biodetection for Chip-Based Portable Diagnosis Systems

Abstract

Keywords

ASJC Scopus subject areas

Access to Document

Other files and links

Fingerprint

Cite this