Gorham Stout disease of the temporal bone with cerebrospinal fluid leak

Pascale Aouad*, Nancy M. Young, Amanda M. Saratsis, Meredith A. Reynolds, Maura E. Ryan

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

Abstract

Gorham Stout disease (GSD) is a rare disease characterized by the proliferation of endothelial lined vessels and replacement of bone by fibrous tissue. The main imaging features are progressive osteolysis and cortical resorption. Temporal bone involvement is rare but presents as a destructive bone lesion that may be misinterpreted as more common lytic processes in the pediatric population, such as infection or Langerhans cell histiocytosis. GSD of the temporal bone is associated with cerebrospinal fluid (CSF) leaks, may present with otorrhea, and can mimic other causes of ear drainage. Here, we report the clinical course, imaging features, and outcomes of a 3-year-old girl with GSD of the temporal bone presenting with CSF leak initially attributed to infection.

Original languageEnglish (US)
JournalChild's Nervous System
DOIs
StateAccepted/In press - 2021

Keywords

  • CSF leak
  • Gorham Stout disease
  • Lymphangioma
  • Osteolysis
  • Temporal bone

ASJC Scopus subject areas

  • Pediatrics, Perinatology, and Child Health
  • Clinical Neurology

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