Abstract
Granulysin is a novel cationic molecule present in the granules of cytotoxic T lymphocytes and natural killer cells. Cytotoxic T lymphocytes have long been associated with graft destruction in transplant rejection. Recent studies implicate granulysin in cell-mediated cytotoxicity, chemoattraction, immune activation and as a potential diagnostic biomarker for transplant rejection.
Original language | English (US) |
---|---|
Pages (from-to) | 1789-1792 |
Number of pages | 4 |
Journal | American Journal of Transplantation |
Volume | 5 |
Issue number | 8 |
DOIs | |
State | Published - Aug 2005 |
Keywords
- Antimicrobial
- Biomarker
- Cytotoxicity
- Granulysin
- Rejection
- Transplantation
ASJC Scopus subject areas
- Immunology and Allergy
- Transplantation
- Pharmacology (medical)