Growth hormone response to growth hormone releasing hormone in depression and schizophrenia

Cecilia A. Peabody*, M. Dhyanne Warner, Edith Markoff, Andrew R. Hoffman, Darrell M. Wilson, John G. Csernansky

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

17 Scopus citations

Abstract

Growth hormone releasing hormone, a 44-amino acid peptide (GHRH-44), was administered (1 mug/kg i.v.) to 6 normal controls, 10 schizophrenic subjects, and 7 depressed subjects. A significantly lower growth hormone (GH) response was found in the schizophrenic and depressed groups. Two molecular forms of GH, 22K GH and 20K GH, were also measured but did not further differentiate the three groups of subjects.

Original languageEnglish (US)
Pages (from-to)269-276
Number of pages8
JournalPsychiatry Research
Volume33
Issue number3
DOIs
StatePublished - Sep 1990

Keywords

  • Growth hormone releasing hormone, growth hormone, depression, schizophrenia

ASJC Scopus subject areas

  • Psychiatry and Mental health
  • Biological Psychiatry

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