Growth rate-dependent accumulation of RNA from plasmid-borne rRNA operons in Escherichia coli

B. S. Stevenson, T. M. Schmidt*

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

28 Scopus citations

Abstract

Inadequate regulation of the expression of additional plasmid-borne rRNA operons in Escherichia coli was exaggerated at slow growth rates, resulting in increases of approximately 100% for RNA concentration and 33% for doubling time. These observations are consistent with the hypothesis that multiple rRNA operons constitute a metabolic burden at slow growth rates.

Original languageEnglish (US)
Pages (from-to)1970-1972
Number of pages3
JournalJournal of bacteriology
Volume180
Issue number7
DOIs
StatePublished - 1998
Externally publishedYes

ASJC Scopus subject areas

  • Microbiology
  • Molecular Biology

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