Guidelines of care for the management of psoriasis and psoriatic arthritis: Section 6. Guidelines of care for the treatment of psoriasis and psoriatic arthritis: Case-based presentations and evidence-based conclusions

Alan Menter, Neil J. Korman, Craig A. Elmets, Steven R. Feldman, Joel M. Gelfand, Kenneth B. Gordon, Alice Gottlieb, John Y.M. Koo, Mark Lebwohl, Craig L. Leonardi, Henry W. Lim, Abby S. Van Voorhees, Karl R. Beutner, Caitriona Ryan, Reva Bhushan*

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

352 Scopus citations

Abstract

Psoriasis is a common, chronic, inflammatory, multisystem disease with predominantly skin and joint manifestations affecting approximately 2% of the population. In the first 5 parts of the AmericanAcademy of Dermatology Psoriasis Guidelines of Care, we have presented evidence supporting the use of topical treatments, phototherapy, traditional systemic agents, and biological therapies for patients with psoriasis and psoriatic arthritis. In this sixth and final section of the Psoriasis Guidelines of Care, we will present cases to illustrate how to practically use these guidelines in specific clinical scenarios. We will describe the approach to treating patients with psoriasis across the entire spectrum of this fascinating disease from mild to moderate to severe, with and without psoriatic arthritis, based on the 5 prior published guidelines. Although specific therapeutic recommendations are given for each of the cases presented, it is important that treatment be tailored to meet individual patients' needs. In addition, we will update the prior 5 guidelines and address gaps in research and care that currently exist, while making suggestions for further studies that could be performed to help address these limitations in our knowledge base.

Original languageEnglish (US)
Pages (from-to)137-174
Number of pages38
JournalJournal of the American Academy of Dermatology
Volume65
Issue number1
DOIs
StatePublished - Jul 2011

Keywords

  • adalimumab
  • alefacept
  • biologics
  • case studies
  • clinical guidelines for psoriasis
  • combination therapy
  • comorbidities
  • dermatology
  • etanercept
  • gaps in knowledge
  • gaps in research
  • golimumab
  • guidelines
  • inflammation
  • infliximab
  • methotrexate
  • narrowband
  • phototherapy
  • psoralen plus ultraviolet A
  • psoriasis
  • psoriatic arthritis
  • skin disease
  • systemic therapy
  • therapeutic recommendations
  • topical treatments
  • traditional systemic therapy
  • tumor necrosis factor-alfa
  • ustekinumab

ASJC Scopus subject areas

  • Dermatology

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