Abstract
H2-M3 is a major histocompatibility complex class Ib molecule that presents N-formylated peptides to specific CD8+T cells. Prokaryotic, but not eukaryotic, translation begins with the addition of N-formyl methionine, suggesting a role for these H2-M3-restricted T cells in response to bacterial infection. Indeed, these cells constitute a non-redundant "early" component of anti-microbial response.
Original language | English (US) |
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Pages (from-to) | 2277-2283 |
Number of pages | 7 |
Journal | Microbes and Infection |
Volume | 8 |
Issue number | 8 |
DOIs | |
State | Published - Jul 2006 |
Keywords
- Listeria
- Major histocompatability complex
- T-Lymphocytes
ASJC Scopus subject areas
- Microbiology
- Immunology
- Infectious Diseases