H2-M3-restricted T cell response to infection

Angela Colmone, Chyung Ru Wang*

*Corresponding author for this work

Research output: Contribution to journalShort survey

17 Scopus citations

Abstract

H2-M3 is a major histocompatibility complex class Ib molecule that presents N-formylated peptides to specific CD8+T cells. Prokaryotic, but not eukaryotic, translation begins with the addition of N-formyl methionine, suggesting a role for these H2-M3-restricted T cells in response to bacterial infection. Indeed, these cells constitute a non-redundant "early" component of anti-microbial response.

Original languageEnglish (US)
Pages (from-to)2277-2283
Number of pages7
JournalMicrobes and Infection
Volume8
Issue number8
DOIs
StatePublished - Jul 1 2006

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Keywords

  • Listeria
  • Major histocompatability complex
  • T-Lymphocytes

ASJC Scopus subject areas

  • Microbiology
  • Immunology
  • Infectious Diseases

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