Hairy cell leukemia

Ronan Swords, Francis Giles*

*Corresponding author for this work

Research output: Contribution to journalReview articlepeer-review

8 Scopus citations

Abstract

Hairy cell leukemia (HCL) is a chronic B-cell lymphoproliferative disorder characterized by pancytopenia and variable infiltration of the reticuloendothelial system with "hairy" lymphocytes. HCL is more common in men than women and has a median age of diagnosis of 52 yr. Typically, patients with HCL respond well to purine analog-based therapy. The purpose of this review will be to establish the current status of HCL with respect to its pathophysiology, diagnosis, management, and future directions.

Original languageEnglish (US)
Pages (from-to)7-15
Number of pages9
JournalMedical Oncology
Volume24
Issue number1
DOIs
StatePublished - Jun 1 2007

Keywords

  • Hairy cell leukemia
  • Pathophysiology
  • Purine analogs
  • Treatment

ASJC Scopus subject areas

  • Hematology
  • Oncology
  • Cancer Research

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