Abstract
Background: Complications related to sickle cell disease (SCD) result in significant declines in health-related quality of life (HRQOL). While hydroxyurea reduces SCD complications, adherence remains suboptimal. The study's objectives were to assess the feasibility of Internet-based electronic assessment of HRQOL in SCD clinic and to examine the relationship between HRQOL and hydroxyurea adherence in adolescents and young adults (AYAs) with SCD. Procedure: A cross-sectional survey was administered on tablets to 34 AYAs (12–22 years old) in a SCD clinic from January through December 2015. Study measures included Patient Reported Outcomes Measurement Information System (PROMIS®) computerized adaptive testing and
| Original language | English (US) |
|---|---|
| Article number | e26369 |
| Journal | Pediatric Blood and Cancer |
| Volume | 64 |
| Issue number | 6 |
| DOIs | |
| State | Published - Jun 1 2017 |
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Keywords
- PROMIS
- adherence
- adolescents
- compliance
- health-related quality of life
- hydroxyurea
- patient-reported outcomes
- patient-reported outcomes measurement information system
- sickle cell anemia
- sickle cell disease
- young adults
ASJC Scopus subject areas
- Pediatrics, Perinatology, and Child Health
- Hematology
- Oncology
Cite this
}
Health-related quality of life and adherence to hydroxyurea in adolescents and young adults with sickle cell disease. / Badawy, Sherif M; Thompson, Alexis A; Lai, Jin-Shei; Penedo, Frank J; Rychlik, Karen; Liem, Robert I.
In: Pediatric Blood and Cancer, Vol. 64, No. 6, e26369, 01.06.2017.Research output: Contribution to journal › Article
TY - JOUR
T1 - Health-related quality of life and adherence to hydroxyurea in adolescents and young adults with sickle cell disease
AU - Badawy, Sherif M
AU - Thompson, Alexis A
AU - Lai, Jin-Shei
AU - Penedo, Frank J
AU - Rychlik, Karen
AU - Liem, Robert I
PY - 2017/6/1
Y1 - 2017/6/1
N2 - Background: Complications related to sickle cell disease (SCD) result in significant declines in health-related quality of life (HRQOL). While hydroxyurea reduces SCD complications, adherence remains suboptimal. The study's objectives were to assess the feasibility of Internet-based electronic assessment of HRQOL in SCD clinic and to examine the relationship between HRQOL and hydroxyurea adherence in adolescents and young adults (AYAs) with SCD. Procedure: A cross-sectional survey was administered on tablets to 34 AYAs (12–22 years old) in a SCD clinic from January through December 2015. Study measures included Patient Reported Outcomes Measurement Information System (PROMIS®) computerized adaptive testing and
AB - Background: Complications related to sickle cell disease (SCD) result in significant declines in health-related quality of life (HRQOL). While hydroxyurea reduces SCD complications, adherence remains suboptimal. The study's objectives were to assess the feasibility of Internet-based electronic assessment of HRQOL in SCD clinic and to examine the relationship between HRQOL and hydroxyurea adherence in adolescents and young adults (AYAs) with SCD. Procedure: A cross-sectional survey was administered on tablets to 34 AYAs (12–22 years old) in a SCD clinic from January through December 2015. Study measures included Patient Reported Outcomes Measurement Information System (PROMIS®) computerized adaptive testing and
KW - PROMIS
KW - adherence
KW - adolescents
KW - compliance
KW - health-related quality of life
KW - hydroxyurea
KW - patient-reported outcomes
KW - patient-reported outcomes measurement information system
KW - sickle cell anemia
KW - sickle cell disease
KW - young adults
UR - http://www.scopus.com/inward/record.url?scp=85006237829&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=85006237829&partnerID=8YFLogxK
U2 - 10.1002/pbc.26369
DO - 10.1002/pbc.26369
M3 - Article
C2 - 27896936
AN - SCOPUS:85006237829
VL - 64
JO - Pediatric Blood and Cancer
JF - Pediatric Blood and Cancer
SN - 1545-5009
IS - 6
M1 - e26369
ER -