Health-Related Quality of Life and Cancer-Related Symptoms during Interdisciplinary Outpatient Rehabilitation for Malignant Brain Tumor

Stacy McCarty*, Sarah M. Eickmeyer, Masha Kocherginsky, Susan Keeshin, Samman Shahpar, Patrick Semik, Alex W.K. Wong

*Corresponding author for this work

Research output: Contribution to journalArticle

4 Citations (Scopus)

Abstract

Objective: The aim of the study was to determine the relationships between functional outcomes, clinical symptoms, and health-related quality of life among patients with malignant brain tumors receiving interdisciplinary outpatient rehabilitation. Design: A prospective study of 49 adults with malignant brain tumors participating in outpatient therapies was performed. Outcome measures included the Functional Assessment of Cancer Therapy-Brain (FACT-Br) for health-related quality of life and the Patient-Reported Outcome Measures Instrument Survey (PROMIS) Depression and Pain Behavior scales measured at admission, discharge, 1 and 3 mos after discharge. Day Rehabilitation Outcome Scale (DayROS), a functional measure, was measured at admission and discharge. Results: The FACT-Br scores, PROMIS pain, and PROMIS depression scores did not significantly change. There were many negative associations seen between FACT-Br and PROMIS depression (all P < .0001) and less associationswith PROMIS pain. Therewas a positive correlation between Day Rehabilitation Outcome Scale and FACT-Br (P = .0058) and a negative association with PROMIS pain (P = .028), but not with PROMIS depression. Therewere no correlations between Day Rehabilitation Outcome Scale gains and change in PROMIS depression, FACTBr total, or PROMIS pain. Conclusions: Health-related quality of life, pain, and depression did not worsen. Patients who reported less depression and pain had better reported health-related quality of life. Level of function was also associated with HRQOL and pain, but not depression.

Original languageEnglish (US)
Pages (from-to)852-860
Number of pages9
JournalAmerican Journal of Physical Medicine and Rehabilitation
Volume96
Issue number12
DOIs
StatePublished - Dec 1 2017

Fingerprint

Brain Neoplasms
Outpatients
Rehabilitation
Quality of Life
Depression
Pain
Neoplasms
Therapeutics
Surveys and Questionnaires
Patient Reported Outcome Measures
Outcome Assessment (Health Care)
Prospective Studies

Keywords

  • Brain Tumor
  • Cancer Rehabilitation
  • Depression
  • Function
  • Pain
  • Quality of Life
  • Rehabilitation

ASJC Scopus subject areas

  • Physical Therapy, Sports Therapy and Rehabilitation
  • Rehabilitation

Cite this

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title = "Health-Related Quality of Life and Cancer-Related Symptoms during Interdisciplinary Outpatient Rehabilitation for Malignant Brain Tumor",
abstract = "Objective: The aim of the study was to determine the relationships between functional outcomes, clinical symptoms, and health-related quality of life among patients with malignant brain tumors receiving interdisciplinary outpatient rehabilitation. Design: A prospective study of 49 adults with malignant brain tumors participating in outpatient therapies was performed. Outcome measures included the Functional Assessment of Cancer Therapy-Brain (FACT-Br) for health-related quality of life and the Patient-Reported Outcome Measures Instrument Survey (PROMIS) Depression and Pain Behavior scales measured at admission, discharge, 1 and 3 mos after discharge. Day Rehabilitation Outcome Scale (DayROS), a functional measure, was measured at admission and discharge. Results: The FACT-Br scores, PROMIS pain, and PROMIS depression scores did not significantly change. There were many negative associations seen between FACT-Br and PROMIS depression (all P < .0001) and less associationswith PROMIS pain. Therewas a positive correlation between Day Rehabilitation Outcome Scale and FACT-Br (P = .0058) and a negative association with PROMIS pain (P = .028), but not with PROMIS depression. Therewere no correlations between Day Rehabilitation Outcome Scale gains and change in PROMIS depression, FACTBr total, or PROMIS pain. Conclusions: Health-related quality of life, pain, and depression did not worsen. Patients who reported less depression and pain had better reported health-related quality of life. Level of function was also associated with HRQOL and pain, but not depression.",
keywords = "Brain Tumor, Cancer Rehabilitation, Depression, Function, Pain, Quality of Life, Rehabilitation",
author = "Stacy McCarty and Eickmeyer, {Sarah M.} and Masha Kocherginsky and Susan Keeshin and Samman Shahpar and Patrick Semik and Wong, {Alex W.K.}",
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AU - McCarty, Stacy

AU - Eickmeyer, Sarah M.

AU - Kocherginsky, Masha

AU - Keeshin, Susan

AU - Shahpar, Samman

AU - Semik, Patrick

AU - Wong, Alex W.K.

PY - 2017/12/1

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N2 - Objective: The aim of the study was to determine the relationships between functional outcomes, clinical symptoms, and health-related quality of life among patients with malignant brain tumors receiving interdisciplinary outpatient rehabilitation. Design: A prospective study of 49 adults with malignant brain tumors participating in outpatient therapies was performed. Outcome measures included the Functional Assessment of Cancer Therapy-Brain (FACT-Br) for health-related quality of life and the Patient-Reported Outcome Measures Instrument Survey (PROMIS) Depression and Pain Behavior scales measured at admission, discharge, 1 and 3 mos after discharge. Day Rehabilitation Outcome Scale (DayROS), a functional measure, was measured at admission and discharge. Results: The FACT-Br scores, PROMIS pain, and PROMIS depression scores did not significantly change. There were many negative associations seen between FACT-Br and PROMIS depression (all P < .0001) and less associationswith PROMIS pain. Therewas a positive correlation between Day Rehabilitation Outcome Scale and FACT-Br (P = .0058) and a negative association with PROMIS pain (P = .028), but not with PROMIS depression. Therewere no correlations between Day Rehabilitation Outcome Scale gains and change in PROMIS depression, FACTBr total, or PROMIS pain. Conclusions: Health-related quality of life, pain, and depression did not worsen. Patients who reported less depression and pain had better reported health-related quality of life. Level of function was also associated with HRQOL and pain, but not depression.

AB - Objective: The aim of the study was to determine the relationships between functional outcomes, clinical symptoms, and health-related quality of life among patients with malignant brain tumors receiving interdisciplinary outpatient rehabilitation. Design: A prospective study of 49 adults with malignant brain tumors participating in outpatient therapies was performed. Outcome measures included the Functional Assessment of Cancer Therapy-Brain (FACT-Br) for health-related quality of life and the Patient-Reported Outcome Measures Instrument Survey (PROMIS) Depression and Pain Behavior scales measured at admission, discharge, 1 and 3 mos after discharge. Day Rehabilitation Outcome Scale (DayROS), a functional measure, was measured at admission and discharge. Results: The FACT-Br scores, PROMIS pain, and PROMIS depression scores did not significantly change. There were many negative associations seen between FACT-Br and PROMIS depression (all P < .0001) and less associationswith PROMIS pain. Therewas a positive correlation between Day Rehabilitation Outcome Scale and FACT-Br (P = .0058) and a negative association with PROMIS pain (P = .028), but not with PROMIS depression. Therewere no correlations between Day Rehabilitation Outcome Scale gains and change in PROMIS depression, FACTBr total, or PROMIS pain. Conclusions: Health-related quality of life, pain, and depression did not worsen. Patients who reported less depression and pain had better reported health-related quality of life. Level of function was also associated with HRQOL and pain, but not depression.

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