Health-related quality of life in chronic myeloid leukemia

Peter C. Trask, David Cella, Christine Powell, Arlene Reisman, Jennifer Whiteley*, Virginia Kelly

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

21 Scopus citations

Abstract

The increased survival associated with treatments for CML emphasize the importance of understanding the HRQOL of newly diagnosed and previously treated CML patients with all phases of disease. Functional Assessment of Cancer Therapy-Leukemia results from a phase 3 and a phase 2 trial are reported for over 900 1st, 2nd, 3rd line CP, AP, and BP patients. Physical Well-being and Leukemia symptoms were worse for patients in later lines of therapy. Individuals with AP and BP CML had poorer HRQOL than individuals with CP CML. HRQOL of CML patients was predominantly consistent with the longitudinal clinical trajectory of the disease.

Original languageEnglish (US)
Pages (from-to)9-13
Number of pages5
JournalLeukemia Research
Volume37
Issue number1
DOIs
StatePublished - Jan 1 2013

Keywords

  • Advanced leukemia
  • Chronic myeloid leukemia
  • Health-related quality of life
  • Patient-reported outcomes

ASJC Scopus subject areas

  • Hematology
  • Oncology
  • Cancer Research

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