Health-related quality of life in small-cell lung cancer: A systematic review on reporting of methods and clinical issues in randomised controlled trials

Efstathios Zikos; Irina Ghislain; Corneel Coens; Divine E. Ediebah; Elizabeth Sloan; Chantal Quinten; Michael Koller; Jan P. van Meerbeeck; Hans Henning Flechtner; Roger Stupp; Athanasios Pallis; Agnes Czimbalmos; Mirjam A G Sprangers; Andrew Bottomley

doi:10.1016/S1470-2045(13)70493-5

Health-related quality of life in small-cell lung cancer: A systematic review on reporting of methods and clinical issues in randomised controlled trials

Efstathios Zikos^*, Irina Ghislain, Corneel Coens, Divine E. Ediebah, Elizabeth Sloan, Chantal Quinten, Michael Koller, Jan P. van Meerbeeck, Hans Henning Flechtner, Roger Stupp, Athanasios Pallis, Agnes Czimbalmos, Mirjam A G Sprangers, Andrew Bottomley

^*Corresponding author for this work

Neurological Surgery

Research output: Contribution to journal › Review article › peer-review

29 Scopus citations

Abstract

Small-cell lung cancer represents about 15% of all lung cancers; increasingly, randomised controlled trials of this disease measure the health-related quality of life of patients. In this Systematic Review we assess the adequacy of reporting of health-related quality-of-life methods in randomised controlled trials of small-cell lung cancer, and the potential effect of this reporting on clinical decision making. Although overall reporting of health-related quality of life was acceptable, improvements are needed to optimise the use of health-related quality of life in randomised controlled trials.

Original language	English (US)
Pages (from-to)	e78-89
Journal	The Lancet Oncology
Volume	15
Issue number	2
DOIs	https://doi.org/10.1016/S1470-2045(13)70493-5
State	Published - Feb 2014

ASJC Scopus subject areas

Oncology

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Zikos, E., Ghislain, I., Coens, C., Ediebah, D. E., Sloan, E., Quinten, C., Koller, M., van Meerbeeck, J. P., Flechtner, H. H., Stupp, R., Pallis, A., Czimbalmos, A., Sprangers, M. A. G., & Bottomley, A. (2014). Health-related quality of life in small-cell lung cancer: A systematic review on reporting of methods and clinical issues in randomised controlled trials. The Lancet Oncology, 15(2), e78-89. https://doi.org/10.1016/S1470-2045(13)70493-5

Zikos, Efstathios ; Ghislain, Irina ; Coens, Corneel ; Ediebah, Divine E. ; Sloan, Elizabeth ; Quinten, Chantal ; Koller, Michael ; van Meerbeeck, Jan P. ; Flechtner, Hans Henning ; Stupp, Roger ; Pallis, Athanasios ; Czimbalmos, Agnes ; Sprangers, Mirjam A G ; Bottomley, Andrew. / Health-related quality of life in small-cell lung cancer : A systematic review on reporting of methods and clinical issues in randomised controlled trials. In: The Lancet Oncology. 2014 ; Vol. 15, No. 2. pp. e78-89.

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title = "Health-related quality of life in small-cell lung cancer: A systematic review on reporting of methods and clinical issues in randomised controlled trials",

abstract = "Small-cell lung cancer represents about 15% of all lung cancers; increasingly, randomised controlled trials of this disease measure the health-related quality of life of patients. In this Systematic Review we assess the adequacy of reporting of health-related quality-of-life methods in randomised controlled trials of small-cell lung cancer, and the potential effect of this reporting on clinical decision making. Although overall reporting of health-related quality of life was acceptable, improvements are needed to optimise the use of health-related quality of life in randomised controlled trials.",

author = "Efstathios Zikos and Irina Ghislain and Corneel Coens and Ediebah, {Divine E.} and Elizabeth Sloan and Chantal Quinten and Michael Koller and {van Meerbeeck}, {Jan P.} and Flechtner, {Hans Henning} and Roger Stupp and Athanasios Pallis and Agnes Czimbalmos and Sprangers, {Mirjam A G} and Andrew Bottomley",

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Zikos, E, Ghislain, I, Coens, C, Ediebah, DE, Sloan, E, Quinten, C, Koller, M, van Meerbeeck, JP, Flechtner, HH, Stupp, R, Pallis, A, Czimbalmos, A, Sprangers, MAG & Bottomley, A 2014, 'Health-related quality of life in small-cell lung cancer: A systematic review on reporting of methods and clinical issues in randomised controlled trials', The Lancet Oncology, vol. 15, no. 2, pp. e78-89. https://doi.org/10.1016/S1470-2045(13)70493-5

Health-related quality of life in small-cell lung cancer : A systematic review on reporting of methods and clinical issues in randomised controlled trials. / Zikos, Efstathios; Ghislain, Irina; Coens, Corneel; Ediebah, Divine E.; Sloan, Elizabeth; Quinten, Chantal; Koller, Michael; van Meerbeeck, Jan P.; Flechtner, Hans Henning; Stupp, Roger; Pallis, Athanasios; Czimbalmos, Agnes; Sprangers, Mirjam A G; Bottomley, Andrew.

In: The Lancet Oncology, Vol. 15, No. 2, 02.2014, p. e78-89.

Research output: Contribution to journal › Review article › peer-review

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AU - Ghislain, Irina

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AU - Ediebah, Divine E.

AU - Sloan, Elizabeth

AU - Quinten, Chantal

AU - Koller, Michael

AU - van Meerbeeck, Jan P.

AU - Flechtner, Hans Henning

AU - Stupp, Roger

AU - Pallis, Athanasios

AU - Czimbalmos, Agnes

AU - Sprangers, Mirjam A G

AU - Bottomley, Andrew

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AB - Small-cell lung cancer represents about 15% of all lung cancers; increasingly, randomised controlled trials of this disease measure the health-related quality of life of patients. In this Systematic Review we assess the adequacy of reporting of health-related quality-of-life methods in randomised controlled trials of small-cell lung cancer, and the potential effect of this reporting on clinical decision making. Although overall reporting of health-related quality of life was acceptable, improvements are needed to optimise the use of health-related quality of life in randomised controlled trials.

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