TY - JOUR
T1 - Heart deformation analysis
T2 - the distribution of regional myocardial motion patterns at left ventricle
AU - Lin, Kai
AU - Meng, Leng
AU - Collins, Jeremy D.
AU - Chowdhary, Varun
AU - Markl, Michael
AU - Carr, James C.
N1 - Funding Information:
This study is supported by grants from the National Institute of Health (R01HL117888 and K01HL121162).
Publisher Copyright:
© 2016, Springer Science+Business Media Dordrecht.
PY - 2017/3/1
Y1 - 2017/3/1
N2 - The aim of the present study was to test the hypothesis that heart deformation analysis (HDA) is able to discriminate regional myocardial motion patterns on the left ventricle (LV). Totally 21 healthy volunteers (15 men and 6 women) without documented cardiovascular diseases were recruited. Cine MRI was performed on those subjects at four-chamber, two-chamber, and short-axis views. The variations of segmental myocardial motion indices of the LV, which were measured with the HDA tool, were investigated. Regional displacement, velocity, strain and strain rate were compared between lateral wall and septal wall using t tests. There are significant variations (CoV = 18.0–72.4%) of myocardial motion indices (average over 21 subjects) among 16 myocardial segments. There are significant differences (p < 0.05) between displacement, velocity, strain and strain rate measured at lateral and septal areas of the LV. In conclusion, HDA is able to present different regional LV motion patterns from multiple aspects in healthy volunteers.
AB - The aim of the present study was to test the hypothesis that heart deformation analysis (HDA) is able to discriminate regional myocardial motion patterns on the left ventricle (LV). Totally 21 healthy volunteers (15 men and 6 women) without documented cardiovascular diseases were recruited. Cine MRI was performed on those subjects at four-chamber, two-chamber, and short-axis views. The variations of segmental myocardial motion indices of the LV, which were measured with the HDA tool, were investigated. Regional displacement, velocity, strain and strain rate were compared between lateral wall and septal wall using t tests. There are significant variations (CoV = 18.0–72.4%) of myocardial motion indices (average over 21 subjects) among 16 myocardial segments. There are significant differences (p < 0.05) between displacement, velocity, strain and strain rate measured at lateral and septal areas of the LV. In conclusion, HDA is able to present different regional LV motion patterns from multiple aspects in healthy volunteers.
KW - Heart deformation analysis
KW - MRI
KW - Myocardial motion pattern
KW - Variations
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U2 - 10.1007/s10554-016-1005-y
DO - 10.1007/s10554-016-1005-y
M3 - Article
C2 - 27783187
AN - SCOPUS:84992327151
SN - 1569-5794
VL - 33
SP - 351
EP - 359
JO - International Journal of Cardiovascular Imaging
JF - International Journal of Cardiovascular Imaging
IS - 3
ER -
