Abstract
The aim of the present study was to test the hypothesis that heart deformation analysis (HDA) is able to discriminate regional myocardial motion patterns on the left ventricle (LV). Totally 21 healthy volunteers (15 men and 6 women) without documented cardiovascular diseases were recruited. Cine MRI was performed on those subjects at four-chamber, two-chamber, and short-axis views. The variations of segmental myocardial motion indices of the LV, which were measured with the HDA tool, were investigated. Regional displacement, velocity, strain and strain rate were compared between lateral wall and septal wall using t tests. There are significant variations (CoV = 18.0–72.4%) of myocardial motion indices (average over 21 subjects) among 16 myocardial segments. There are significant differences (p < 0.05) between displacement, velocity, strain and strain rate measured at lateral and septal areas of the LV. In conclusion, HDA is able to present different regional LV motion patterns from multiple aspects in healthy volunteers.
Original language | English (US) |
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Pages (from-to) | 351-359 |
Number of pages | 9 |
Journal | International Journal of Cardiovascular Imaging |
Volume | 33 |
Issue number | 3 |
DOIs | |
State | Published - Mar 1 2017 |
Funding
This study is supported by grants from the National Institute of Health (R01HL117888 and K01HL121162).
Keywords
- Heart deformation analysis
- MRI
- Myocardial motion pattern
- Variations
ASJC Scopus subject areas
- Cardiology and Cardiovascular Medicine
- Radiology Nuclear Medicine and imaging