TY - JOUR
T1 - Heart Failure in Africa, Asia, the Middle East and South America
T2 - The INTER-CHF study
AU - On behalf of the INTER-CHF Investigators (Appendix 1)
AU - Dokainish, Hisham
AU - Teo, Koon
AU - Zhu, Jun
AU - Roy, Ambuj
AU - Alhabib, Khalid F.
AU - Elsayed, Ahmed
AU - Palileo-Villaneuva, Lia
AU - Lopez-Jaramillo, Patricio
AU - Karaye, Kamilu
AU - Yusoff, Khalid
AU - Orlandini, Andres
AU - Sliwa, Karen
AU - Mondo, Charles
AU - Lanas, Fernando
AU - Prabhakaran, Dorairaj
AU - Badr, Amr
AU - Elmaghawry, Mohamed
AU - Damasceno, Albertino
AU - Tibazarwa, Kemi
AU - Belley-Cote, Emilie
AU - Balasubramanian, Kumar
AU - Yacoub, Magdi H.
AU - Huffman, Mark D.
AU - Harkness, Karen
AU - Grinvalds, Alex
AU - McKelvie, Robert
AU - Yusuf, Salim
N1 - Publisher Copyright:
© 2015 Elsevier Ireland Ltd. All rights reserved.
PY - 2016/2/1
Y1 - 2016/2/1
N2 - Background There are few data on heart failure (HF) patients from Africa, Asia, the Middle East and South America. Methods INTER-CHF is a prospective study that enrolled HF patients in 108 centers in 16 countries from 2012 to 2014. Consecutive ambulatory or hospitalized adult patients with HF were enrolled. Baseline data were recorded on sociodemographics, clinical characteristics, HF etiology and treatments. Age- and sex-adjusted results are reported. Results We recruited 5813 HF patients: mean(SE) age = 59(0.2) years, 39% female, 65% outpatients, 31% from rural areas, 26% with HF with preserved ejection fraction, with 1294 from Africa, 2661 from Asia, 1000 from the Middle-East, and 858 from South America. Participants from Africa - closely followed by Asians - were younger, had lower literacy levels, and were less likely to have health or medication insurance or be on beta-blockers compared with participants from other regions, but were most likely to be in NYHA class IV. Participants from South America were older, had higher insurance and literacy levels, and, along with Middle Eastern participants, were more likely to be on beta-blockers, but had the lowest proportion in NYHA IV. Ischemic heart disease was the most common HF etiology in all regions except Africa where hypertensive heart disease was most common. Conclusions INTER-CHF describes significant regional variability in socioeconomic and clinical factors, etiologies and treatments in HF patients from Africa, Asia, the Middle East and South America. Opportunities exist for improvement in health/medication insurance rates and proportions of patients on beta blockers, particularly in Africa and Asia.
AB - Background There are few data on heart failure (HF) patients from Africa, Asia, the Middle East and South America. Methods INTER-CHF is a prospective study that enrolled HF patients in 108 centers in 16 countries from 2012 to 2014. Consecutive ambulatory or hospitalized adult patients with HF were enrolled. Baseline data were recorded on sociodemographics, clinical characteristics, HF etiology and treatments. Age- and sex-adjusted results are reported. Results We recruited 5813 HF patients: mean(SE) age = 59(0.2) years, 39% female, 65% outpatients, 31% from rural areas, 26% with HF with preserved ejection fraction, with 1294 from Africa, 2661 from Asia, 1000 from the Middle-East, and 858 from South America. Participants from Africa - closely followed by Asians - were younger, had lower literacy levels, and were less likely to have health or medication insurance or be on beta-blockers compared with participants from other regions, but were most likely to be in NYHA class IV. Participants from South America were older, had higher insurance and literacy levels, and, along with Middle Eastern participants, were more likely to be on beta-blockers, but had the lowest proportion in NYHA IV. Ischemic heart disease was the most common HF etiology in all regions except Africa where hypertensive heart disease was most common. Conclusions INTER-CHF describes significant regional variability in socioeconomic and clinical factors, etiologies and treatments in HF patients from Africa, Asia, the Middle East and South America. Opportunities exist for improvement in health/medication insurance rates and proportions of patients on beta blockers, particularly in Africa and Asia.
KW - Epidemiology
KW - Global health
KW - Heart failure
KW - Registry
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U2 - 10.1016/j.ijcard.2015.11.183
DO - 10.1016/j.ijcard.2015.11.183
M3 - Article
C2 - 26657608
AN - SCOPUS:84955280854
SN - 0167-5273
VL - 204
SP - 133
EP - 141
JO - International Journal of Cardiology
JF - International Journal of Cardiology
ER -