Heart failure in African Americans: Disparities can be overcome

Alok Sharma, Monica Colvin-Adams*, Clyde W. Yancy

*Corresponding author for this work

Research output: Contribution to journalArticle

34 Scopus citations

Abstract

African Americans are disproportionately affected by heart failure, with a high prevalence at an early age. Hypertension, diabetes, obesity, and chronic kidney disease are all common in African Americans and all predispose to heart failure. Neurohormonal imbalances, endothelial dysfunction, genetic polymorphisms, and socioeconomic factors also contribute. In general, the same evidencebased treatment guidelines that apply to white patients with heart failure also apply to African Americans. However, the combination of hydralazine and isosorbide dinitrate is advised specifically for African Americans.

Original languageEnglish (US)
Pages (from-to)301-311
Number of pages11
JournalCleveland Clinic journal of medicine
Volume81
Issue number5
DOIs
StatePublished - 2014

ASJC Scopus subject areas

  • Medicine(all)

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