Hemolytic uremic syndrome and crescentic glomerulonephritis complicating childhood nephrosis

A. M. Krensky, J. R. Ingelfinger, W. E. Grupe, S. Rosen

Research output: Contribution to journalArticlepeer-review

16 Scopus citations


Three children with nephrotic syndrome and focal segmental glomerulosclerosis and/or mesangial proliferation on renal biopsy developed the sudden onset of renal failure, microangiopathic hemolytic anemia, and thrombocytopenia. Two of the three children developed crescentic glomerulonephritis and never regained renal function while the third showed no change from his original histologic pattern and also developed chronic renal failure. These cases suggest an association between the lipoid nephrosis - focal segmental glomerulosclerosis group of glomerular diseases and crescentic glomerulonephritis, and may represent an unusual pathway in the evolution of childhood nephrosis.

Original languageEnglish (US)
Pages (from-to)99-106
Number of pages8
JournalClinical Nephrology
Issue number2
StatePublished - Jan 1 1983

ASJC Scopus subject areas

  • Nephrology


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