Keyphrases
Hyperoxaluria
100%
RNA Interference
100%
Lactate Dehydrogenase
100%
Nedosiran
100%
Oxalate
50%
Nonclinical Data
50%
Potential Therapeutics
25%
Liver
25%
Therapeutic Potential
25%
Nonhuman Primate
25%
Liver-specific
25%
Healthy Volunteers
25%
Rare Genetic Disease
25%
Overproduction
25%
Clinical Data
25%
Urinary Oxalate
25%
Therapeutic Mechanism
25%
Result-oriented
25%
Substantial Evidence
25%
Randomized Controlled Trial
25%
Muscle Function
25%
Interconversion
25%
Lactate
25%
Unintended Consequences
25%
Drug Dependence
25%
Placebo Groups
25%
Creatine Kinase
25%
Renal Damage
25%
Plasma Lactate
25%
RNA Interference Therapy
25%
Renal Excretion
25%
Pyruvate Kinase
25%
Liver Manifestations
25%
Musculoskeletal Adverse Event
25%
Glyoxylate
25%
Glyoxylate Metabolism
25%
Medicine and Dentistry
Primary Hyperoxaluria
100%
Lactate Dehydrogenase
100%
LDHA
100%
RNAI
100%
Oxalic Acid
37%
Lactic Acid
25%
Glyoxylic Acid
25%
Adverse Event
12%
Genetic Disorder
12%
Single Drug Dose
12%
Muscle Function
12%
Pyruvic Acid
12%
Target Tissue
12%
Creatine Kinase
12%
Kidney Injury
12%
Urinary Excretion
12%
Placebo
12%
RNAi Therapeutics
12%
Randomized Controlled Trial
12%
Urinary System
12%
Volunteer
12%
Pyruvate Kinase
12%
Pharmacology, Toxicology and Pharmaceutical Science
Oxalosis 1
100%
Lactate Dehydrogenase
100%
Lactic Acid
50%
Glyoxylic Acid
50%
Normal Human
25%
Randomized Controlled Trial
25%
Renal Excretion
25%
Adverse Event
25%
Placebo
25%
Genetic Disorder
25%
Kidney Injury
25%
Pyruvic Acid
25%
Creatine Kinase
25%
Pyruvate Kinase
25%
Biochemistry, Genetics and Molecular Biology
LDHA
100%
Lactate Dehydrogenase
100%
RNAI
100%
Metabolic Pathway
12%
Genetic Disorder
12%
Randomized Controlled Trial
12%
Target Tissue
12%
Muscle Function
12%
Normal Human
12%
Single Drug Dose
12%
Urinary Excretion
12%
Lactate Blood Level
12%
Creatine Kinase
12%
Pyruvate Kinase
12%