Hepatitis C Genotype 3 Infection: Pathogenesis and Treatment Horizons

Haripriya Maddur*, Steven L Flamm

*Corresponding author for this work

Research output: Contribution to journalReview articlepeer-review

3 Scopus citations


Genotype 3 hepatitis C infection is the second most common genotype worldwide and accounts for most infections in Southeast Asia. It is a particularly ominous genotype because it has been linked to increased mortality, specifically increased late-stage liver events, accelerated development of hepatic fibrosis, and an increased risk of hepatocellular carcinoma. As new treatment regimens for hepatitis C have been emerging, treatment of genotype 3 often requires longer treatment duration with decreased response rates as compared with other genotypes.

Original languageEnglish (US)
Pages (from-to)645-657
Number of pages13
JournalClinics in liver disease
Issue number4
StatePublished - Nov 1 2017


  • Accelerated fibrosis
  • Genotype 3
  • Hepatic steatosis
  • Hepatitis C
  • Hepatocellular carcinoma

ASJC Scopus subject areas

  • Hepatology


Dive into the research topics of 'Hepatitis C Genotype 3 Infection: Pathogenesis and Treatment Horizons'. Together they form a unique fingerprint.

Cite this