Hepatoblastoma in children with congenital portosystemic shunts

Timothy B Lautz*, Sonam A. Shah, Riccardo A Superina

*Corresponding author for this work

Research output: Contribution to journalArticle

10 Citations (Scopus)

Abstract

Two children developed hepatoblastoma concurrent with congenital portosystemic shunts (PSSs) (Abernethy malformations). Both underwent operative ligation of their PSSs. One received concurrent tumor resection, whereas the other was deemed initially unresectable and underwent biopsy followed by neoadjuvant chemotherapy. Although benign hepatic masses, such as focal nodular hyperplasia and nodular regenerative hyperplasia, are common in patients with Abernethy malformations, malignant tumors have also been documented and should always be considered in the differential diagnosis of a patient with a congenital PSS and a hepatic mass.

Original languageEnglish (US)
Pages (from-to)542-545
Number of pages4
JournalJournal of pediatric gastroenterology and nutrition
Volume62
Issue number4
DOIs
StatePublished - Jan 1 2016

Fingerprint

Surgical Portasystemic Shunt
Hepatoblastoma
Focal Nodular Hyperplasia
Liver
Hyperplasia
Ligation
Neoplasms
Differential Diagnosis
Biopsy
Drug Therapy

Keywords

  • Abernethy malformation
  • Hepatoblastoma
  • Portosystemic shunt

ASJC Scopus subject areas

  • Pediatrics, Perinatology, and Child Health
  • Gastroenterology

Cite this

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abstract = "Two children developed hepatoblastoma concurrent with congenital portosystemic shunts (PSSs) (Abernethy malformations). Both underwent operative ligation of their PSSs. One received concurrent tumor resection, whereas the other was deemed initially unresectable and underwent biopsy followed by neoadjuvant chemotherapy. Although benign hepatic masses, such as focal nodular hyperplasia and nodular regenerative hyperplasia, are common in patients with Abernethy malformations, malignant tumors have also been documented and should always be considered in the differential diagnosis of a patient with a congenital PSS and a hepatic mass.",
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Hepatoblastoma in children with congenital portosystemic shunts. / Lautz, Timothy B; Shah, Sonam A.; Superina, Riccardo A.

In: Journal of pediatric gastroenterology and nutrition, Vol. 62, No. 4, 01.01.2016, p. 542-545.

Research output: Contribution to journalArticle

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