Hepatotoxic Reactions in a Patient Treated with Etretinate

Virginia C. Weiss; Dennis P. West; Rollie Ackerman; Lisa A. Robinson

doi:10.1001/archderm.1984.01650370110022

Hepatotoxic Reactions in a Patient Treated with Etretinate

Virginia C. Weiss^*, Dennis P. West, Rollie Ackerman, Lisa A. Robinson

^*Corresponding author for this work

Dermatology

Research output: Contribution to journal › Article › peer-review

31 Scopus citations

Abstract

• Hepatotoxic reactions and eosinophilia developed in a 74-year-old woman who had been treated with an aromatic retinoid compound, etretinate, for severe psoriasis palmaris et plantaris. Rapid improvement in her condition followed discontinuation of the drug therapy. Liver enzyme elevations recurred after reinstitution of etretinate therapy; these levels quickly returned to normal after the drug therapy was again discontinued. Our patient's reaction to etretinate may have been a hypersensitivity reaction.

Original language	English (US)
Pages (from-to)	104-106
Number of pages	3
Journal	Archives of Dermatology
Volume	120
Issue number	1
DOIs	https://doi.org/10.1001/archderm.1984.01650370110022
State	Published - Jan 1984

ASJC Scopus subject areas

Dermatology

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10.1001/archderm.1984.01650370110022

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abstract = "• Hepatotoxic reactions and eosinophilia developed in a 74-year-old woman who had been treated with an aromatic retinoid compound, etretinate, for severe psoriasis palmaris et plantaris. Rapid improvement in her condition followed discontinuation of the drug therapy. Liver enzyme elevations recurred after reinstitution of etretinate therapy; these levels quickly returned to normal after the drug therapy was again discontinued. Our patient's reaction to etretinate may have been a hypersensitivity reaction.",

author = "Weiss, {Virginia C.} and West, {Dennis P.} and Rollie Ackerman and Robinson, {Lisa A.}",

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AU - Weiss, Virginia C.

AU - West, Dennis P.

AU - Ackerman, Rollie

AU - Robinson, Lisa A.

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Y1 - 1984/1

N2 - • Hepatotoxic reactions and eosinophilia developed in a 74-year-old woman who had been treated with an aromatic retinoid compound, etretinate, for severe psoriasis palmaris et plantaris. Rapid improvement in her condition followed discontinuation of the drug therapy. Liver enzyme elevations recurred after reinstitution of etretinate therapy; these levels quickly returned to normal after the drug therapy was again discontinued. Our patient's reaction to etretinate may have been a hypersensitivity reaction.

AB - • Hepatotoxic reactions and eosinophilia developed in a 74-year-old woman who had been treated with an aromatic retinoid compound, etretinate, for severe psoriasis palmaris et plantaris. Rapid improvement in her condition followed discontinuation of the drug therapy. Liver enzyme elevations recurred after reinstitution of etretinate therapy; these levels quickly returned to normal after the drug therapy was again discontinued. Our patient's reaction to etretinate may have been a hypersensitivity reaction.

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Hepatotoxic Reactions in a Patient Treated with Etretinate

Abstract

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