Abstract
In this article the medications that have been shown to increase rates of drug-induced liver injury in patients with cirrhosis and the important drug-drug interactions in recipients of liver transplantation are reviewed. In general, the risk of drug-induced liver injury in patients with cirrhosis does not seem to be higher when compared with the noncirrhotic population. There are, however, 2 classes of agents that have been implicated-medications used to treat tuberculosis and medications used to treat human immunodeficiency virus infection. However, with careful monitoring, even significant interactions can be effectively managed.
Original language | English (US) |
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Pages (from-to) | 737-747 |
Number of pages | 11 |
Journal | Clinics in liver disease |
Volume | 17 |
Issue number | 4 |
DOIs | |
State | Published - Nov 2013 |
Keywords
- Calcineurin
- DILI
- Immunosuppressives
- Medication
ASJC Scopus subject areas
- Hepatology