Hepatotoxicity and drug interactions in liver transplant candidates and recipients

Neehar D. Parikh, Josh Levitsky*

*Corresponding author for this work

Research output: Contribution to journalReview article

6 Scopus citations

Abstract

In this article the medications that have been shown to increase rates of drug-induced liver injury in patients with cirrhosis and the important drug-drug interactions in recipients of liver transplantation are reviewed. In general, the risk of drug-induced liver injury in patients with cirrhosis does not seem to be higher when compared with the noncirrhotic population. There are, however, 2 classes of agents that have been implicated-medications used to treat tuberculosis and medications used to treat human immunodeficiency virus infection. However, with careful monitoring, even significant interactions can be effectively managed.

Original languageEnglish (US)
Pages (from-to)737-747
Number of pages11
JournalClinics in Liver Disease
Volume17
Issue number4
DOIs
StatePublished - Nov 1 2013

Keywords

  • Calcineurin
  • DILI
  • Immunosuppressives
  • Medication

ASJC Scopus subject areas

  • Hepatology

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