Herpes Simplex Virus Associated With Recurrent Stevens-Johnson Syndrome: A Management Strategy

Paul F. Detjen, Roy Patterson*, Gary A. Noskin, John P. Phair, Stephen O. Loyd

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

18 Scopus citations

Abstract

We describe a 36-year-old man with recurrent Stevens-Johnson syndrome, which became progressively more severe over a 13-year period. His episodes were apparently preceded by herpes simplex virus oral mucosal infections. A management protocol, including immediate therapy with acyclovir and prednisone at the onset of herpes simplex virus oropharyngitis, is outlined. This management strategy has successfully prevented four subsequent episodes of progression to Stevens-Johnson syndrome. Thus, Stevens-Johnson syndrome associated with herpes simplex virus may be prevented by early use of acyclovir and prednisone.

Original languageEnglish (US)
Pages (from-to)1513-1516
Number of pages4
JournalArchives of Internal Medicine
Volume152
Issue number7
DOIs
StatePublished - Jul 1992

ASJC Scopus subject areas

  • Internal Medicine

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