Heterodimeric JAK-STAT activation as a mechanism of persistence to JAK2 inhibitor therapy

Priya Koppikar*, Neha Bhagwat, Outi Kilpivaara, Taghi Manshouri, Mazhar Adli, Todd Hricik, Fan Liu, Lindsay M. Saunders, Ann Mullally, Omar Abdel-Wahab, Laura Leung, Abby Weinstein, Sachie Marubayashi, Aviva Goel, Mithat Gonen, Zeev Estrov, Benjamin L. Ebert, Gabriela Chiosis, Stephen D. Nimer, Bradley E. BernsteinSrdan Verstovsek, Ross L. Levine

*Corresponding author for this work

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Keyphrases

Immunology and Microbiology

Medicine and Dentistry

Pharmacology, Toxicology and Pharmaceutical Science

Biochemistry, Genetics and Molecular Biology

Neuroscience