TY - JOUR
T1 - Hibernoma with inflammatory features
T2 - A description of a new variant
AU - Streich, Lukas
AU - Yang, Ximing
N1 - Publisher Copyright:
© 2020 The Authors
PY - 2020/11
Y1 - 2020/11
N2 - Hibernoma is an uncommon benign tumor arising from brown fat. These tumors are well-described in the literature, and occur throughout the body with the majority of cases arising in the thigh, shoulder, and upper back, with some in the retroperitoneum. Several morphologic variants have been described, including typical, spindle, lipoma-like, and myxoid. The overlap with a well-differentiated liposarcoma/atypical lipomatous tumor is well-known, and the two lesions can be differentiated by immunostaining and in-situ hybridization for MDM2. In this report, we describe a case of hibernoma with a dense lymphoplasmacytic infiltrate arising in the retroperitoneum, a morphologic variant not previously described in the literature.
AB - Hibernoma is an uncommon benign tumor arising from brown fat. These tumors are well-described in the literature, and occur throughout the body with the majority of cases arising in the thigh, shoulder, and upper back, with some in the retroperitoneum. Several morphologic variants have been described, including typical, spindle, lipoma-like, and myxoid. The overlap with a well-differentiated liposarcoma/atypical lipomatous tumor is well-known, and the two lesions can be differentiated by immunostaining and in-situ hybridization for MDM2. In this report, we describe a case of hibernoma with a dense lymphoplasmacytic infiltrate arising in the retroperitoneum, a morphologic variant not previously described in the literature.
KW - Genitourinary pathology
KW - Hibernoma
KW - Liposarcoma
KW - Pathology
KW - Renal pathology
KW - Sarcoma
KW - Sarcoma pathology
KW - Soft tissue pathology
KW - Surgical pathology
UR - http://www.scopus.com/inward/record.url?scp=85091952103&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=85091952103&partnerID=8YFLogxK
U2 - 10.1016/j.ehpc.2020.200429
DO - 10.1016/j.ehpc.2020.200429
M3 - Article
AN - SCOPUS:85091952103
SN - 2214-3300
VL - 22
JO - Human Pathology: Case Reports
JF - Human Pathology: Case Reports
M1 - 200429
ER -